{"id":9568,"date":"2025-03-12T15:37:39","date_gmt":"2025-03-12T15:37:39","guid":{"rendered":"https:\/\/csiag.eu\/?p=9568"},"modified":"2025-10-26T16:58:08","modified_gmt":"2025-10-26T16:58:08","slug":"esencialni-oleje-proc-funguji","status":"publish","type":"post","link":"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/","title":{"rendered":"Esenci\u00e1ln\u00ed oleje - pro\u010d funguj\u00ed?"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_87_1 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Obsah<\/p>\n<span class=\"ez-toc-title-toggle\"><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Riechen_und_Schmecken\" >V\u016fn\u011b a chu\u0165<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Wie_funktionieren_Schmerzrezeptoren\" >Jak funguj\u00ed receptory bolesti?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Welche_Rezeptoren_sind_relevant\" >Kter\u00e9 receptory jsou relevantn\u00ed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Schmerz_bekampft_Schmerz\" >Bolest bojuje proti bolesti?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Chemische_Wirkung_auf_Duft-Rezeptoren\" >Chemick\u00fd \u00fa\u010dinek na (pachov\u00e9) receptory<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Riechrezeptoren_vs_Duftrezeptoren\" >\u010cichov\u00e9 receptory vs. \u010dichov\u00e9 receptory<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Die_Zelle\" >Bu\u0148ka<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#DNA_DNS\" >DNA (DNA)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#mRNA\" >mRNA<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Transkription\" >P\u0159epis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Translation\" >P\u0159eklad<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Exozytose_nur_fur_sekretierte_Proteine\" >Exocyt\u00f3za (pouze u vylu\u010dovan\u00fdch protein\u016f)<\/a><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Der_GABA-Rezeptor\" >Receptor GABA<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Das_Protein_%E2%80%93_der_Duftrezeptor\" >Protein - receptor pachu<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#EIN_Tropfen\" >JEDNA kapka<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Gen_%E2%80%93_ein-_oder_ausgeschaltet\" >Gen - zapnut\u00fd nebo vypnut\u00fd<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Diagnostik_%E2%80%A6\" >Diagnostika ...<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#%E2%80%A6_Therapie\" >... Terapie<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Unterschied_%E2%80%93_Atherische_Ole_und_Hydrolate\" >Rozd\u00edl - esenci\u00e1ln\u00ed oleje a hydrol\u00e1ty<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Praxis-Beispiele\" >Praktick\u00e9 p\u0159\u00edklady<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Wie_finden_Spermien_den_kurzesten_Weg_zur_Samenzelle\" >Jak spermie najdou nejkrat\u0161\u00ed cestu ke spermatick\u00e9 bu\u0148ce?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Magen-Darm-Trakt\" >Gastrointestin\u00e1ln\u00ed trakt<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Haut_und_Haare\" >K\u016f\u017ee a vlasy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-24\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Herz\" >Srdce<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-25\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Lunge\" >Pl\u00edce<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-26\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Prostata\" >Prostata<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-27\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Blase\" >Bublina<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-28\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Kolon\" >St\u0159eva<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-29\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Liste_aller_Olfaktorischen_Rezeptoren\" >Seznam v\u0161ech \u010dichov\u00fdch receptor\u016f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-30\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Worauf_basiert_die_antibakterielle_antivirale_Wirkung\" >Na \u010dem je zalo\u017een antibakteri\u00e1ln\u00ed\/antivirov\u00fd \u00fa\u010dinek?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-31\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Bakterien\" >Bakterie<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-32\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Viren\" >Viry<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-33\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Wie_verstecken_sich_Viren\" >Jak se viry skr\u00fdvaj\u00ed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-34\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Signalwege\" >Sign\u00e1ln\u00ed dr\u00e1hy<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-35\" href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/#Quellenangaben\" >Odkazy<\/a><\/li><\/ul><\/nav><\/div>\n<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Doba \u010dten\u00ed<\/span> <span class=\"rt-time\"> 12<\/span> <span class=\"rt-label rt-postfix\">minuty<\/span><\/span>\n<p class=\"wp-block-paragraph\">Pro\u010d esenci\u00e1ln\u00ed oleje funguj\u00ed? Tato ot\u00e1zka je opr\u00e1vn\u011bn\u00e1 a odpov\u011b\u010f na ni je nesm\u00edrn\u011b hlubok\u00e1 a ne\u010dekan\u011b vzru\u0161uj\u00edc\u00ed.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">V\u016fn\u011b - ka\u017ed\u00fd asi zn\u00e1 vonn\u00e9 lampy, jako jsou vonn\u00e9 sv\u00ed\u010dky, jejich\u017e v\u016fn\u011b nen\u00ed v\u017edy vn\u00edm\u00e1na jako p\u0159\u00edjemn\u00e1, ale \u010dasto zp\u016fsobuje bolesti hlavy, nep\u0159\u00edjemn\u00e9 pocity a dokonce nevolnost, zejm\u00e9na u syntetick\u00fdch vonn\u00fdch olej\u016f.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">V\u016fn\u011b sv\u00e1d\u011bj\u00ed nejen v podob\u011b d\u00e1msk\u00fdch parf\u00e9m\u016f, ale tak\u00e9 ve vlaku, v hotelech, obchodn\u00edch domech atd., aby z\u00e1kazn\u00edky uvedly do p\u0159\u00edjemn\u00e9ho rozpolo\u017een\u00ed a nal\u00e1kaly je tak k lep\u0161\u00edmu hodnocen\u00ed nebo n\u00e1kupu v\u00fdrobk\u016f t\u00edm, \u017ee je rozptyluj\u00ed prost\u0159ednictv\u00edm klimatiza\u010dn\u00edch syst\u00e9m\u016f v prostor\u00e1ch.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">V\u016fn\u011b se pou\u017e\u00edvaj\u00ed v nemocnic\u00edch ke sn\u00ed\u017een\u00ed spot\u0159eby analgetik (l\u00e9k\u016f proti bolesti) nebo hypnotik (pr\u00e1\u0161k\u016f na span\u00ed) a tak\u00e9 v paliativn\u00ed p\u00e9\u010di k \u00falev\u011b nemocn\u00fdch.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">P\u016fvod \u00e9terick\u00fdch olej\u016f spo\u010d\u00edv\u00e1 v imunitn\u00edm syst\u00e9mu rostlin, kter\u00e9 se jimi chr\u00e1n\u00ed p\u0159ed pred\u00e1tory, pl\u00edsn\u011bmi, bakteriemi a viry, tj. maj\u00ed protipl\u00eds\u0148ov\u00fd, antibakteri\u00e1ln\u00ed a antivirov\u00fd \u00fa\u010dinek. Nap\u0159\u00edklad \u00e9terick\u00fd olej z m\u00e1ty peprn\u00e9 je tak siln\u00fd, \u017ee by po\u0161kodil samotnou rostlinu, kdyby nebyl zabalen v mal\u00fdch kapsl\u00edch na listech, kter\u00e9 uvol\u0148uj\u00ed svou \u00fa\u010dinnou l\u00e1tku pouze p\u0159i dotyku.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">P\u0159esto\u017ee jsou takov\u00e9 aplikace dnes ji\u017e zn\u00e1m\u00e9 a zejm\u00e9na komer\u010dn\u00ed podniky by je nepraktikovaly, kdyby nebyla prok\u00e1z\u00e1na \u00fa\u010dinnost t\u011bchto ekonomicky orientovan\u00fdch opat\u0159en\u00ed, z\u016fst\u00e1v\u00e1 ot\u00e1zka: jak je to mo\u017en\u00e9 - co je z\u00e1kladem tohoto \u00fa\u010dinku u lid\u00ed?<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Riechen_und_Schmecken\"><\/span>V\u016fn\u011b a chu\u0165<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">M\u016f\u017eeme n\u011bkoho \"c\u00edtit\" nebo sp\u00ed\u0161e ne..., vzpomenout si na z\u00e1\u017eitky s babi\u010dkou, pokud k n\u00e1m byla p\u0159\u00e1telsk\u00e1, pozitivn\u011b, jakmile vn\u00edm\u00e1me nap\u0159. levandulovou v\u016fni, kterou pou\u017e\u00edvala do s\u00e1\u010dk\u016f ve sk\u0159\u00edni na ochranu p\u0159ed moly. Pokud v\u0161ak byla babi\u010dka sp\u00ed\u0161e nep\u0159\u00edjemn\u00e1 osoba, rychle odejdeme, jakmile tuto v\u016fni, kterou nyn\u00ed vn\u00edm\u00e1me jako nep\u0159\u00edjemnou, zaznamen\u00e1me.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">N\u00e1\u0161 nos nefunguje v\u017edy jako objektivn\u00ed \u010dichov\u00fd org\u00e1n a jeho vn\u00edm\u00e1n\u00ed v\u016fn\u00ed je ovlivn\u011bno na\u0161imi individu\u00e1ln\u00edmi zku\u0161enostmi.<br><br>\u010cichov\u00e9 receptory podporuj\u00ed chu\u0165ov\u00e9 bu\u0148ky p\u0159i vn\u00edm\u00e1n\u00ed sladk\u00e9ho, kysel\u00e9ho, slan\u00e9ho, ho\u0159k\u00e9ho a slan\u00e9ho. Naproti tomu \u0161tiplavost nen\u00ed chu\u0165 v prav\u00e9m slova smyslu, ale bolestiv\u00fd podn\u011bt, kter\u00fd vyvol\u00e1v\u00e1 nap\u0159. chilli, \u010dern\u00fd pep\u0159 prost\u0159ednictv\u00edm sv\u00fdch chemick\u00fdch slo\u017eek. <em>Kapsaicin<\/em> nebo <em>Piperin<\/em> a zp\u016fsoben\u00e9 <em>Trigemin\u00e1ln\u00ed nerv<\/em>-Bolest se p\u0159en\u00e1\u0161\u00ed z l\u00edcn\u00edho nervu do mozku, kde je definov\u00e1na jako bolest.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Trojklann\u00fd nerv, kter\u00fd je aktivov\u00e1n podn\u011bty bolesti, teploty nebo chemoreceptory, p\u0159en\u00e1\u0161\u00ed sign\u00e1ly bolesti do talamu, kter\u00fd je p\u0159ed\u00e1v\u00e1 do r\u016fzn\u00fdch oblast\u00ed mozku, v\u010detn\u011b somatosenzorick\u00e9 k\u016fry v temenn\u00edm laloku (horn\u00ed \u010d\u00e1st lebky, kter\u00e1 se nach\u00e1z\u00ed nad t\u00fdln\u00edm lalokem a za \u010deln\u00edm lalokem; je zodpov\u011bdn\u00e1 za lokalizaci bolesti a jej\u00ed kvalitativn\u00ed hodnocen\u00ed, stejn\u011b jako za somatosenzorick\u00e9 vn\u00edm\u00e1n\u00ed a koordinaci ruka-oko).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pokud tedy chceme bojovat proti bolesti, m\u016f\u017eeme p\u0159ij\u00edt s n\u00e1padem vypnout trojklann\u00fd nerv. Proto\u017ee v\u0161ak nerv nezpracov\u00e1v\u00e1 pouze pocit bolesti, ale tak\u00e9 teplo, chlad a chemick\u00e9 podn\u011bty, tyto funkce by ji\u017e neexistovaly. Pop\u00e1leniny nebo omrzliny bychom nevn\u00edmali stejn\u011b jako chemick\u00e9 pop\u00e1leniny. Mo\u017en\u00e1 praktick\u00e9, ale ne rozumn\u00e9.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Wie_funktionieren_Schmerzrezeptoren\"><\/span>Jak funguj\u00ed receptory bolesti?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Receptory bolesti jsou lokalizov\u00e1ny na nervov\u00fdch bu\u0148k\u00e1ch a obsahuj\u00ed iontov\u00e9 kan\u00e1ly (<em>TRP<\/em> - <em>P\u0159echodn\u00fd receptorov\u00fd potenci\u00e1l<\/em>), kter\u00e9 se otev\u00edraj\u00ed a aktivuj\u00ed v\u00fd\u0161e uveden\u00fdmi podn\u011bty.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bu\u0148ka, kter\u00e1 je norm\u00e1ln\u011b z\u00e1porn\u011b nabit\u00e1 v porovn\u00e1n\u00ed s okol\u00edm, a m\u00e1 tedy klidov\u00fd potenci\u00e1l, je depolarizov\u00e1na p\u0159\u00edlivem kladn\u011b nabit\u00fdch iont\u016f a zv\u00fd\u0161\u00ed se na ak\u010dn\u00ed potenci\u00e1l.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">P\u0159ekro\u010den\u00ed definovan\u00e9 prahov\u00e9 hodnoty iniciuje sign\u00e1l, kter\u00fd je p\u0159en\u00e1\u0161en nervov\u00fdmi vl\u00e1kny do mozku jako bolestiv\u00fd podn\u011bt.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Welche_Rezeptoren_sind_relevant\"><\/span>Kter\u00e9 receptory jsou relevantn\u00ed?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Trpa1<\/em>-receptory reaguj\u00ed na chlad a chemick\u00e9 l\u00e1tky (<em>Eukalyptol, sko\u0159icov\u00fd olej, z\u00e1zvorov\u00fd olej, h\u0159eb\u00ed\u010dkov\u00fd olej<\/em> (<em>Eugenol<\/em>)), ale jsou tak\u00e9 aktivov\u00e1ny z\u00e1n\u011btliv\u00fdmi podn\u011bty nebo po\u0161kozen\u00edm tk\u00e1n\u011b a zp\u016fsobuj\u00ed mozku sign\u00e1l bolesti.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Trpv1<\/em>-receptory reaguj\u00ed na vysok\u00e9 teploty (ho\u0159en\u00ed) nebo chemick\u00e9 podn\u011bty (<em>Thymol<\/em>, <em>Kapsaicin<\/em> - ABC) se stejn\u00fdm v\u00fdsledkem.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Na str\u00e1nk\u00e1ch <em>Trpm8<\/em>-receptor je naopak spou\u0161t\u011bn chladov\u00fdmi podn\u011bty (&lt; 28 \u00b0C), ale tak\u00e9 chemick\u00fdmi l\u00e1tkami, jako jsou nap\u0159. <em>Mentol<\/em>kter\u00fd se rovn\u011b\u017e objevuje jako bolestiv\u00fd podn\u011bt.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A <em>Trpv4-<\/em>receptor reaguje na teploty 25 ... 35 \u00b0C, zat\u00edmco <em>Trpv3<\/em> pro rozsah 30 ... 40 \u00b0C, <em>Trpv1<\/em> zahrnuje teploty &gt; 43 \u00b0C a <em>Trpv2<\/em> &gt; 52 \u00b0C.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Schmerz_bekampft_Schmerz\"><\/span>Bolest bojuje proti bolesti?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">To, co na prvn\u00ed pohled zn\u00ed absurdn\u011b, se v praxi ukazuje jako skute\u010dnost. Ale jak je to mo\u017en\u00e9?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Na jedn\u00e9 stran\u011b pln\u00ed v\u00fd\u0161e zm\u00edn\u011bn\u00e9 receptory bolesti varovnou funkci t\u00edm, \u017ee upozor\u0148uj\u00ed t\u011blo na nebezpe\u010dn\u00e9 teploty a zprost\u0159edkov\u00e1vaj\u00ed odpov\u00eddaj\u00edc\u00ed vjemy, kter\u00e9 umo\u017e\u0148uj\u00ed lidem p\u0159ijmout protiopat\u0159en\u00ed.<br>Tak\u017ee rychle sund\u00e1te ruku z hork\u00e9 plot\u00fdnky nebo z \u017e\u00edrav\u00e9 tekutiny, n\u011bco si obl\u00e9knete, pokud je p\u0159\u00edli\u0161 chladno, samovoln\u011b zadr\u017e\u00edte dech v p\u0159\u00edtomnosti \u0161tiplav\u011b p\u00e1chnouc\u00edch plyn\u016f. Na \"p\u00e1livou\" feferonku nebo chilli reaguje t\u011blo p\u00e1len\u00edm, extr\u00e9mn\u011b bolestiv\u00fdm pocitem a zv\u00fd\u0161enou tvorbou slin, aby se co nejrychleji zbavilo dr\u00e1\u017ediv\u00e9 l\u00e1tky, a tak d\u00e1le.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Na druh\u00e9 stran\u011b intenzivn\u00ed bolestiv\u00e9 podn\u011bty zp\u016fsobuj\u00ed uvol\u0148ov\u00e1n\u00ed endogenn\u00edch l\u00e1tek, jako jsou nap\u0159. <em>Endorfiny, enkefaliny, serotonin <\/em>a<em> Prostaglandiny<\/em>a\u017e po opi\u00e1ty. Pokud by toto uvol\u0148ov\u00e1n\u00ed nebylo zastaveno, proto\u017ee podn\u011bt bolesti je st\u00e1le p\u0159\u00edtomen, do\u0161lo by k nadm\u011brn\u00fdm a \u0161kodliv\u00fdm reakc\u00edm.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Proto se receptory bolesti po n\u011bkolika minut\u00e1ch vypnou a po ur\u010ditou dobu ji\u017e nemohou b\u00fdt stimulov\u00e1ny. T\u00edm se tak\u00e9 zastav\u00ed uvol\u0148ov\u00e1n\u00ed p\u0159\u00edslu\u0161n\u00fdch l\u00e1tek.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Chemische_Wirkung_auf_Duft-Rezeptoren\"><\/span>Chemick\u00fd \u00fa\u010dinek na (pachov\u00e9) receptory<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Zn\u00e1m\u00fd <em>ABC om\u00edtky<\/em> je zn\u00e1m\u00fd sv\u00fdm p\u00e1len\u00edm. <em>Kapsaicin<\/em> aktivuje <em>Receptor Trpv1<\/em>. Ten p\u0159en\u00e1\u0161\u00ed sign\u00e1l bolesti vyvolan\u00e9 teplem do mozku. Ten pak lokalizuje oblast \"bolav\u00fdch zad\" a zp\u016fsob\u00ed roz\u0161\u00ed\u0159en\u00ed c\u00e9v, aby se zv\u00fd\u0161il p\u0159\u00edvod krve, a t\u00edm se odvedlo teplo, proto\u017ee je tam - \u00fadajn\u011b - \"horko\".<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Terapeuticky zam\u00fd\u0161len\u00fd \u00fa\u010dinek zv\u00fd\u0161en\u00e9ho krevn\u00edho ob\u011bhu umo\u017e\u0148uje \u00fa\u010dinn\u011bj\u0161\u00ed odstran\u011bn\u00ed odpadn\u00edch l\u00e1tek ze ztvrdl\u00e9ho, a tedy bolestiv\u00e9ho svalu a jeho op\u011btovn\u00e9 uvoln\u011bn\u00ed. \u00da\u010dinek zp\u016fsoben\u00fd <em>Kapsaicin<\/em> vyvolan\u00e1 bolest po chv\u00edli ustoup\u00ed, ale pocit tepla p\u0159etrv\u00e1v\u00e1 n\u011bkolik hodin.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\"Teplo\", kter\u00e9 mozek vn\u00edm\u00e1, poch\u00e1z\u00ed v\u00fdhradn\u011b z p\u016fsoben\u00ed <em>Kapsaicin<\/em>-chemick\u00e9 l\u00e1tky vyvolan\u00e9 <em>Receptorov\u00fd podn\u011bt<\/em>ale ne ze skute\u010dn\u00e9ho fyzick\u00e9ho oteplen\u00ed.<br>Vn\u00edman\u00e9 \"zv\u00fd\u0161en\u00e9\" teplo pod <em>ABC om\u00edtky<\/em> je jen o m\u00e1lo vy\u0161\u0161\u00ed ne\u017e samotn\u00e1 t\u011blesn\u00e1 teplota. Je to proto, \u017ee vazodilatace zvy\u0161uje pr\u016ftok krve a oblast k\u016f\u017ee je proto o n\u011bco teplej\u0161\u00ed ne\u017e okoln\u00ed tk\u00e1\u0148, kter\u00e1 je m\u00e9n\u011b intenzivn\u011b prokrven\u00e1.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Dal\u0161\u00ed \u00fa\u010dinn\u00e1 l\u00e1tka, a to <em>Eugenol<\/em> z h\u0159eb\u00ed\u010dkov\u00e9ho oleje znaj\u00ed n\u011bkte\u0159\u00ed sou\u010dasn\u00edci z n\u00e1v\u0161t\u011bv u zuba\u0159e p\u0159i nesnesiteln\u00e9 bolesti zub\u016f - trojklann\u00fd nerv pos\u00edl\u00e1 sv\u00e9 p\u0159\u00e1telsk\u00e9 pozdravy ...<br><em>Eugenol<\/em> se v\u00e1\u017ee na <em>Trpm8<\/em>-a blokuje tak p\u0159enos bolestiv\u00fdch podn\u011bt\u016f.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Podobn\u011b <em>Mentol<\/em> a <em>M\u00e1tov\u00fd olej<\/em> na adrese <em>Receptor Trpm8<\/em>zejm\u00e9na u chronick\u00e9 bolesti, proto\u017ee <em>Trpm8<\/em> se zhruba po 5 minut\u00e1ch vypne a p\u0159estane reagovat na dal\u0161\u00ed bolestiv\u00e9 podn\u011bty.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Linalool<\/em> a <em>Linalyl acet\u00e1t<\/em>ob\u011b hlavn\u00ed \u00fa\u010dinn\u00e9 l\u00e1tky levandulov\u00e9ho oleje jsou v krvi zjistiteln\u00e9 po jemn\u00e9 mas\u00e1\u017ei levandulov\u00fdm olejem ji\u017e po 5 minut\u00e1ch (<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7043716\/\" target=\"_blank\" rel=\"noopener\">Zdroj:<\/a>), jen o 20 minut pozd\u011bji vrcholov\u00e9 koncentrace 121 ng\/ml <em>Linalool<\/em> a 100 ng\/ml <em>Linalyl acet\u00e1t<\/em> m\u011b\u0159iteln\u00e9.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Podobn\u011b inhalace levandulov\u00e9 silice rozpra\u0161ovan\u00e9 pomoc\u00ed difuz\u00e9ru vede ke stejn\u00fdm koncentrac\u00edm jako lok\u00e1ln\u00ed aplikace po perkut\u00e1nn\u00edm po\u017eit\u00ed, jako ve v\u00fd\u0161e uveden\u00e9m p\u0159\u00edpad\u011b.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ob\u011b \u00fa\u010dinn\u00e9 l\u00e1tky maj\u00ed sedativn\u00ed, anxiolytick\u00e9, relaxa\u010dn\u00ed a analgetick\u00e9 \u00fa\u010dinky, <em>Linalyl acet\u00e1t<\/em> dal\u0161\u00ed antimikrobi\u00e1ln\u00ed \u00fa\u010dinek.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Riechrezeptoren_vs_Duftrezeptoren\"><\/span>\u010cichov\u00e9 receptory vs. \u010dichov\u00e9 receptory<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Krom\u011b nosn\u00edch \u010dichov\u00fdch receptor\u016f existuj\u00ed tak\u00e9 \u010dichov\u00e9 receptory (proteiny specificky produkovan\u00e9 bu\u0148kou). Ty se vyskytuj\u00ed ve v\u0161ech org\u00e1nech, nej\u010dast\u011bji ve varlatech (s p\u0159ibli\u017en\u011b 55 aktivn\u00edmi geny z celkov\u00fdch 138 dostupn\u00fdch) a nejm\u00e9n\u011b \u010dasto v j\u00e1trech (pouze s jedn\u00edm genem z celkov\u00fdch 19 sou\u010dasn\u00fdch).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Proto\u017ee se molekuly \u00e9terick\u00fdch olej\u016f vst\u0159eb\u00e1vaj\u00ed perkut\u00e1nn\u011b, inhala\u010dn\u011b nebo vnit\u0159n\u011b (oleje v kapsl\u00edch) p\u0159es tr\u00e1vic\u00ed trakt a d\u00edky sv\u00e9 molekul\u00e1rn\u00ed velikosti mohou b\u00fdt detekov\u00e1ny v krvi a dokonce proch\u00e1zej\u00ed hematoencefalickou bari\u00e9rou, nen\u00ed p\u0159ekvapiv\u00e9, \u017ee se jejich \u00fa\u010dinek projevuje i ve v\u0161ech org\u00e1nech t\u011bla.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ale jak p\u0159esn\u011b to funguje?<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Die_Zelle\"><\/span>Bu\u0148ka<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Ka\u017ed\u00e1 bu\u0148ka v lidsk\u00e9m t\u011ble se skl\u00e1d\u00e1 z j\u00e1dra (<em>Nucleus<\/em>), kter\u00fd obsahuje kompletn\u00ed sadu gen\u016f, na okoln\u00ed geny. <em>Cytoplazma<\/em>v n\u011bm\u017e prob\u00edhaj\u00ed v\u0161echny bun\u011b\u010dn\u00e9 procesy, a v\u0161eobj\u00edmaj\u00edc\u00ed, selektivn\u011b polopropustn\u00fd <em>Bun\u011b\u010dn\u00e1 membr\u00e1na<\/em>Bun\u011b\u010dn\u00e1 membr\u00e1na je receptorov\u00e1 membr\u00e1na, p\u0159es kterou proteiny tvo\u0159\u00edc\u00ed kan\u00e1ly umo\u017e\u0148uj\u00ed v\u00fdm\u011bnu l\u00e1tek, a receptory na bun\u011b\u010dn\u00e9 membr\u00e1n\u011b slou\u017e\u00ed k mezibun\u011b\u010dn\u00e9 komunikaci.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"DNA_DNS\"><\/span>DNA (DNA)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">DNA (deoxyribonukleov\u00e1 kyselina -&gt; <em>Deoxyribonukleov\u00e1 kyselina<\/em>) obsahuje informace pot\u0159ebn\u00e9 pro strukturu, funkci a reprodukci v\u0161ech bun\u011bk a organism\u016f.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"855\" height=\"215\" src=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-2.png\" alt=\"\" class=\"wp-image-9608\" style=\"width:327px;height:auto\" srcset=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-2.png 855w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-2-300x75.png 300w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-2-768x193.png 768w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-2-18x5.png 18w\" sizes=\"(max-width: 855px) 100vw, 855px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">P\u0159ibli\u017en\u011b 98% gen\u016f je deaktivov\u00e1no, pouze 20 000 ... 25 000 gen\u016f je aktivn\u00edch a slou\u017e\u00ed k synt\u00e9ze protein\u016f.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"mRNA\"><\/span>mRNA<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">mRNA (<em>messengerov\u00e1 RNA<\/em>) je kopie informa\u010dn\u00edho \u0159et\u011bzce obsa\u017een\u00e9ho v DNA pro v\u00fdrobu protein\u016f, kter\u00e9 n\u00e1sledn\u011b \u0159\u00edd\u00ed funkce v t\u011ble.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Transkription\"><\/span>P\u0159epis<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Podobn\u011b jako u bambusu, jeho\u017e kmen se opakovan\u011b zahu\u0161\u0165uje, je i zde po\u010d\u00e1tek (<em>Promot\u00e9r<\/em>) a konec (<em>Sekvence Termin\u00e1tor<\/em> - Ten tak\u00e9 funguje jako sp\u00edna\u010d, kter\u00fd zap\u00edn\u00e1 nebo vyp\u00edn\u00e1 gen) sekvence genu, kter\u00e1 m\u00e1 b\u00fdt p\u0159e\u010dtena a zkop\u00edrov\u00e1na.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Abyste z\u00edskali p\u0159\u00edstup ke kop\u00edrovan\u00e9mu \u00faseku, mus\u00ed b\u00fdt \"\u017eeb\u0159\u00edk\" p\u0159ipojen ke kop\u00edrovan\u00e9mu \u00faseku prost\u0159ednictv\u00edm p\u0159\u00edkazu <em>Promot\u00e9r<\/em> ozna\u010den\u00e1 pozice. To se prov\u00e1d\u00ed pomoc\u00ed enzymu <em>RNA polymer\u00e1za<\/em>kter\u00fd rovn\u011b\u017e vytvo\u0159\u00ed kopii. Pokud enzym dos\u00e1hne <em>Sekvence Termin\u00e1tor<\/em>zastav\u00ed kop\u00edrov\u00e1n\u00ed.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"855\" height=\"216\" src=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-3.png\" alt=\"\" class=\"wp-image-9609\" style=\"width:329px;height:auto\" srcset=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-3.png 855w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-3-300x76.png 300w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-3-768x194.png 768w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-3-18x5.png 18w\" sizes=\"(max-width: 855px) 100vw, 855px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">Vznikl\u00e1 molekula mRNA se odd\u011bl\u00ed od DNA, odd\u011blen\u00e9 vl\u00e1kno se op\u011bt uzav\u0159e a mRNA se uvoln\u00ed z bun\u011b\u010dn\u00e9ho j\u00e1dra do bun\u011b\u010dn\u00e9ho prost\u0159ed\u00ed. <em>Cytoplazma<\/em> odv\u00e1d\u011bny ven.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Translation\"><\/span>P\u0159eklad<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Nyn\u00ed v <em>Cytoplazma<\/em> mRNA m\u016f\u017ee b\u00fdt nyn\u00ed pou\u017eita jako \u0161ablona pro biosynt\u00e9zu b\u00edlkovin v pr\u016fb\u011bhu <em>P\u0159eklad<\/em> slou\u017eit. P\u0159eklad se \"p\u0159ekl\u00e1d\u00e1\" do <em>Ribosomy<\/em> d\u0159\u00edve vytvo\u0159en\u00e9 kopie genetick\u00e9 informace mRNA do funk\u010dn\u00ed sekvence aminokyselin, kter\u00e1 v t\u011ble vyvol\u00e1 zam\u00fd\u0161len\u00fd \u00fa\u010dinek v podob\u011b b\u00edlkoviny.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img decoding=\"async\" width=\"803\" height=\"1024\" src=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-5-803x1024.png\" alt=\"\" class=\"wp-image-9611\" style=\"width:333px;height:auto\" srcset=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-5-803x1024.png 803w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-5-235x300.png 235w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-5-768x979.png 768w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-5-9x12.png 9w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-5.png 865w\" sizes=\"(max-width: 803px) 100vw, 803px\" \/><\/figure>\n<\/div>\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Exozytose_nur_fur_sekretierte_Proteine\"><\/span>Exocyt\u00f3za (pouze u vylu\u010dovan\u00fdch protein\u016f)<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Tak\u017ee protein, kter\u00fd m\u00e1 p\u016fsobit mimo bu\u0148ku, jako nap\u0159. <em>Hormony<\/em>, <em>Enzymy<\/em> nebo <em>Protil\u00e1tky<\/em>mus\u00ed b\u00fdt transportov\u00e1n mimo bu\u0148ku. Tento proces se naz\u00fdv\u00e1 <em>Exocyt\u00f3za<\/em>.<br>\u00dakol p\u0159epravy pln\u00ed tzv. (specializovan\u00e9) <em>Vezikuly<\/em>. Na str\u00e1nk\u00e1ch . <em>Vezikuly<\/em> se spoj\u00ed s bun\u011b\u010dnou membr\u00e1nou a uvoln\u00ed sv\u016fj obsah do bun\u011bk. <em>Extracelul\u00e1rn\u00ed prostor<\/em>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Der_GABA-Rezeptor\"><\/span>Receptor GABA<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">GABA (GAmma-AminoButyric Acid) receptor je nejd\u016fle\u017eit\u011bj\u0161\u00ed funk\u010dn\u00ed inhibi\u010dn\u00ed neurotransmiter. Existuje ve dvou variant\u00e1ch: GABA_A jako \u010dist\u011b iontov\u011b kan\u00e1lov\u00fd receptor s rychl\u00fdm \u00fa\u010dinkem a GABA_B jako receptor s rychl\u00fdm \u00fa\u010dinkem. <em>metabotropn\u00ed<\/em> Receptor, pomalej\u0161\u00ed, ale d\u00e9le p\u016fsob\u00edc\u00ed.<br>Metabotropn\u00ed receptory obvykle pat\u0159\u00ed do rodiny receptor\u016f sp\u0159a\u017een\u00fdch s G proteiny (GPCR) a iniciuj\u00ed procesy prost\u0159ednictv\u00edm sekund\u00e1rn\u00edch posl\u016f nebo intracelul\u00e1rn\u00edch sign\u00e1ln\u00edch drah.<br>Kdy\u017e se na takov\u00fd receptor nav\u00e1\u017ee neurotransmiter nebo jin\u00fd sign\u00e1l, aktivuje se G protein. To spust\u00ed kask\u00e1du dal\u0161\u00edch biochemick\u00fdch reakc\u00ed, kter\u00e9 mohou ovlivnit r\u016fzn\u00e9 bun\u011b\u010dn\u00e9 procesy, jako je aktivace enzym\u016f nebo uvol\u0148ov\u00e1n\u00ed sekund\u00e1rn\u00edch posl\u016f, jako je cAMP nebo IP3.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Je c\u00edlem mnoha l\u00e9k\u016f, ale tak\u00e9 \u00e9terick\u00fdch olej\u016f, pokud jde o dosa\u017een\u00ed spasmolytick\u00fdch, anxiolytick\u00fdch \u00fa\u010dink\u016f nebo v podstat\u011b regulaci vzru\u0161ivosti nervov\u00fdch bun\u011bk.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tento efekt je zp\u016fsoben p\u0159\u00edlivem z\u00e1porn\u011b nabit\u00fdch chloridov\u00fdch iont\u016f. Jak bylo uvedeno v\u00fd\u0161e, st\u00e1le negativn\u011bj\u0161\u00ed bun\u011b\u010dn\u00fd potenci\u00e1l vede ke sn\u00ed\u017een\u00ed ak\u010dn\u00edho potenci\u00e1lu. To je pos\u00edleno l\u00e1tkami, kter\u00e9 se v\u00e1\u017eou na GABA receptor, co\u017e vede k uklid\u0148uj\u00edc\u00edm, relaxa\u010dn\u00edm a \u00fazkost zm\u00edr\u0148uj\u00edc\u00edm \u00fa\u010dink\u016fm.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Das_Protein_%E2%80%93_der_Duftrezeptor\"><\/span>Protein - receptor pachu<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">B\u00edlkovina vznikl\u00e1 translac\u00ed slou\u017e\u00ed jako pachov\u00fd receptor. Jakmile se na receptor nav\u00e1\u017ee molekula pachu, spust\u00ed se prost\u0159ednictv\u00edm p\u0159\u00edslu\u0161n\u00e9ho sign\u00e1lu specifick\u00fd \u00fa\u010dinek.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zde je v\u00fd\u0161e popsan\u00fd postup v grafick\u00e9 podob\u011b v pln\u00e9m rozsahu:<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"979\" src=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-1-1024x979.png\" alt=\"\" class=\"wp-image-9606\" srcset=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-1-1024x979.png 1024w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-1-300x287.png 300w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-1-768x734.png 768w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-1-1536x1468.png 1536w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-1-2048x1958.png 2048w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-1-13x12.png 13w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">A jak najde molekula v\u016fn\u011b receptor v\u016fn\u011b, kdy\u017e lidsk\u00e9 t\u011blo tvo\u0159\u00ed p\u0159ibli\u017en\u011b 37,2 bilionu (!) bun\u011bk - 37 200 000 000 000 000 000, pokud je to desetinn\u00e9 \u010d\u00edslo? Kolik \u00e9terick\u00e9ho oleje je vlastn\u011b pot\u0159eba, aby ka\u017ed\u00e1 bu\u0148ka m\u011bla k dispozici pouze jednu molekulu \u00e9terick\u00e9ho oleje?<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"EIN_Tropfen\"><\/span>JEDNA kapka<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Jedin\u00e1 kapka grapefruitov\u00e9ho oleje obsahuje 226,92 bilionu molekul oleje. P\u0159i rozd\u011blen\u00ed mezi p\u0159ibli\u017en\u011b 37,2 bilionu t\u011blesn\u00fdch bun\u011bk (v z\u00e1vislosti na hmotnosti a velikosti) p\u0159ipad\u00e1 na jednu bu\u0148ku 6,1 milionu molekul oleje!<br>To znamen\u00e1, \u017ee \u017e\u00e1dn\u00e1 t\u011blesn\u00e1 bu\u0148ka se nemus\u00ed b\u00e1t, \u017ee by ji molekuly jedin\u00e9 kapky esenci\u00e1ln\u00edho oleje p\u0159ehl\u00e9dly.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Nyn\u00ed by m\u011blo b\u00fdt jasn\u00e9, \u017ee \u00e9terick\u00e9 oleje mohou zas\u00e1hnout ka\u017ed\u00fd org\u00e1n v t\u011ble a ovlivnit tak jeho funkci.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Gen_%E2%80%93_ein-_oder_ausgeschaltet\"><\/span>Gen - zapnut\u00fd nebo vypnut\u00fd<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Pokud se analyzuj\u00ed vzorky tk\u00e1n\u00ed z lidsk\u00fdch org\u00e1n\u016f, zjist\u00ed se, \u017ee se v nich zap\u00ednaj\u00ed a vyp\u00ednaj\u00ed geny pachov\u00fdch receptor\u016f. Podle toho, kter\u00e9 geny jsou zapnut\u00e9 nebo vypnut\u00e9, je mo\u017en\u00e9 ur\u010dit, o kter\u00fd org\u00e1n se jedn\u00e1. To znamen\u00e1, \u017ee ka\u017ed\u00e1 bu\u0148ka t\u00e9ho\u017e org\u00e1nu m\u00e1 aktivovan\u00e9 nebo deaktivovan\u00e9 stejn\u00e9 geny.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Po\u010det zapnut\u00fdch gen\u016f v tk\u00e1ni umo\u017e\u0148uje vyvodit z\u00e1v\u011bry o zdravotn\u00edm stavu tk\u00e1n\u011b. Ve srovn\u00e1n\u00ed s nemocnou tk\u00e1n\u00ed m\u00e1 zdrav\u00e1 tk\u00e1\u0148 zapnuto relativn\u011b m\u00e1lo gen\u016f a pouze na velmi kr\u00e1tk\u00e9 \u010dasov\u00e9 intervaly (bled\u0161\u00ed barevn\u00e9 ozna\u010den\u00ed, viz obr\u00e1zek n\u00ed\u017ee).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zapnut\u00fd gen pachov\u00e9ho receptoru znamen\u00e1 prob\u00edhaj\u00edc\u00ed produkci protein\u016f. \u010c\u00edm d\u00e9le je zapnut\u00fd, t\u00edm v\u00edce protein\u016f se exprimuje.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Diagnostik_%E2%80%A6\"><\/span>Diagnostika ...<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Pokud je zapnuto v\u00fdrazn\u011b v\u00edce pachov\u00fdch receptor\u016f, a to p\u0159\u00edpadn\u011b na del\u0161\u00ed dobu (tmav\u0161\u00ed barevn\u00e9 ozna\u010den\u00ed) ne\u017e obvykle, sv\u011bd\u010d\u00ed to o onemocn\u011bn\u00ed tk\u00e1n\u011b nebo n\u00e1dorov\u00e9 aktivit\u011b, jak ukazuje tento p\u0159\u00edklad u 21 vzork\u016f tk\u00e1n\u011b z <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5818398\/\" target=\"_blank\" rel=\"noreferrer noopener\">karcinom prsu<\/a> ve srovn\u00e1n\u00ed se 7 zdrav\u00fdmi vzorky.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"654\" src=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-6-1024x654.png\" alt=\"\" class=\"wp-image-9621\" srcset=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-6-1024x654.png 1024w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-6-300x192.png 300w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-6-768x491.png 768w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-6-1536x981.png 1536w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-6-2048x1308.png 2048w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-6-18x12.png 18w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Frekven\u010dn\u00ed rozlo\u017een\u00ed 26 pachov\u00fdch receptor\u016f v 21 tk\u00e1n\u00edch karcinomu prsu ve srovn\u00e1n\u00ed se zdravou tk\u00e1n\u00ed<\/figcaption><\/figure>\n<\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"77\" src=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-7-1024x77.png\" alt=\"\" class=\"wp-image-9622\" srcset=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-7-1024x77.png 1024w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-7-300x23.png 300w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-7-768x58.png 768w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-7-1536x116.png 1536w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-7-18x1.png 18w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-7.png 1622w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">FPKM (fragmenty na kilob\u00e1zi transkriptu na milion mapovan\u00fdch \u010dten\u00ed) <\/figcaption><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\"><em><a href=\"https:\/\/docs.gdc.cancer.gov\/Encyclopedia\/pages\/FPKM\/\" target=\"_blank\" rel=\"noreferrer noopener\">FPKM<\/a><\/em> je metrika pro kvantifikaci exprese gen\u016f. Jedn\u00e1 se o normalizovanou m\u00edru, kter\u00e1 umo\u017e\u0148uje porovn\u00e1vat expresi gen\u016f mezi r\u016fzn\u00fdmi vzorky nebo podm\u00ednkami.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Marker je l\u00e1tka, kter\u00e1 se vyskytuje pouze ve zv\u00fd\u0161en\u00e9 koncentraci nebo je p\u0159\u00edtomna pouze v p\u0159\u00edpad\u011b, \u017ee je tk\u00e1\u0148 nemocn\u00e1 nebo posti\u017een\u00e1 n\u00e1dorem.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E2%80%A6_Therapie\"><\/span>... Terapie<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Prof. Dr. Dr. Dr. med. habil. Hanns Hatt (Ruhr University Bochum (RUB)) se ji\u017e des\u00edtky let zab\u00fdv\u00e1 molekul\u00e1rn\u00ed a bun\u011b\u010dnou senzorickou fyziologi\u00ed, v\u00fdzkumem v\u016fn\u00ed a chut\u00ed, je autorem, p\u0159edn\u00e1\u0161\u00ed a publikuje v\u00fdsledky sv\u00e9ho v\u00fdzkumu, nap\u0159. \"<a href=\"https:\/\/journals.physiology.org\/doi\/full\/10.1152\/physrev.00013.2017?rfr_dat=cr_pub++0pubmed&amp;url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org\" target=\"_blank\" rel=\"noreferrer noopener\">Lidsk\u00e9 pachov\u00e9 receptory: Nov\u00e9 funkce bun\u011bk mimo nos<\/a>\u201e.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img decoding=\"async\" width=\"595\" height=\"1024\" src=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/Mensch_Hatt-595x1024.png\" alt=\"\" class=\"wp-image-9638\" style=\"width:415px;height:auto\" srcset=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/Mensch_Hatt-595x1024.png 595w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/Mensch_Hatt-174x300.png 174w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/Mensch_Hatt-768x1321.png 768w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/Mensch_Hatt-7x12.png 7w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/Mensch_Hatt.png 800w\" sizes=\"(max-width: 595px) 100vw, 595px\" \/><figcaption class=\"wp-element-caption\">Lidsk\u00e1 tk\u00e1\u0148 a odpov\u00eddaj\u00edc\u00ed bun\u011b\u010dn\u00e9 linie, u nich\u017e byla prok\u00e1z\u00e1na funk\u010dnost pachov\u00fdch receptor\u016f.<\/figcaption><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">V\u00fd\u0161e uveden\u00fd obr\u00e1zek byl p\u0159evzat z v\u00fd\u0161e uveden\u00e9ho dokumentu a krom\u011b mnoha dal\u0161\u00edch v\u00fdsledk\u016f v\u00fdzkumu a publikac\u00ed (viz odkazy) ukazuje, \u017ee \u00e9terick\u00e9 oleje lze \u00fa\u010dinn\u011b vyu\u017e\u00edt v diagnostice a terapii d\u00edky prok\u00e1zan\u00e9 existenci a aktivit\u011b \u010dichov\u00fdch receptor\u016f (OR), kter\u00e9 se v t\u011bchto tk\u00e1n\u00edch nach\u00e1zej\u00ed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Unterschied_%E2%80%93_Atherische_Ole_und_Hydrolate\"><\/span>Rozd\u00edl - esenci\u00e1ln\u00ed oleje a hydrol\u00e1ty<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Hydrol\u00e1ty jsou vedlej\u0161\u00edm produktem destilace vodn\u00ed p\u00e1ry za \u00fa\u010delem z\u00edsk\u00e1n\u00ed esenci\u00e1ln\u00edch olej\u016f. Zat\u00edmco \u00e9terick\u00e9 oleje NEJSOU rozpustn\u00e9 ve vod\u011b, ale v tuc\u00edch (<em>lipofiln\u00ed<\/em>), hydrol\u00e1ty jsou l\u00e1tky rozpustn\u00e9 ve vod\u011b (<em>hydrofiln\u00ed<\/em>) Slo\u017een\u00ed.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Hydrol\u00e1ty lze na poko\u017eku nan\u00e1\u0161et ne\u0159ed\u011bn\u00e9 a maj\u00ed jemnou, ale stejn\u011b t\u011bkavou v\u016fni.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Jejich \u00fa\u010dinek je v podstat\u011b podobn\u00fd \u00fa\u010dinku \u00e9terick\u00fdch olej\u016f (v men\u0161\u00ed m\u00ed\u0159e), nap\u0159. protiz\u00e1n\u011btliv\u00fd, antiseptick\u00fd, chladiv\u00fd, antiperspira\u010dn\u00ed, expektora\u010dn\u00ed, uklid\u0148uj\u00edc\u00ed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Praxis-Beispiele\"><\/span>Praktick\u00e9 p\u0159\u00edklady<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Ve\u0161ker\u00e1 teorie je \u0161ediv\u00e1, zde sp\u00ed\u0161e barvit\u00e1, ale n\u011bkolik p\u0159\u00edklad\u016f z lidsk\u00e9 praxe, ze \u017eivota samotn\u00e9ho, p\u016fsobiv\u011bji vyjad\u0159uje to, co teorie pod\u00e1v\u00e1 jen v\u00edcem\u00e9n\u011b su\u0161e.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">V\u0161echny p\u0159\u00edklady najdete v prezentaci \"<a href=\"https:\/\/www.youtube.com\/watch?v=DmHgZKiU1LE\" target=\"_blank\" rel=\"noreferrer noopener\">L\u00e9\u010den\u00ed pomoc\u00ed v\u016fn\u00ed<\/a>\" od 04.06.2019, Nadace Johannese Gutenberga, obdarovan\u00fd profesor Dr. Dr. Dr. med. habil. Hanns Hatt na Por\u00farsk\u00e9 univerzit\u011b v Bochumi.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Wie_finden_Spermien_den_kurzesten_Weg_zur_Samenzelle\"><\/span>Jak spermie najdou nejkrat\u0161\u00ed cestu ke spermatick\u00e9 bu\u0148ce?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ve spermi\u00edch se nach\u00e1z\u00ed a\u017e 20 z 53 pachov\u00fdch receptor\u016f. Ve vagin\u00e1ln\u00edm sekretu je zn\u00e1mo 15 pach\u016f, podle kter\u00fdch se spermie orientuj\u00ed (v\u010detn\u011b <em>M\u011b\u0161\u0165ansk\u00e9<\/em>; Antagonista: <em>Undecanal<\/em>)) a vede ke zdvojn\u00e1soben\u00ed jejich rychlosti pohybu. Pokud jsou spermie vystaveny p\u016fsoben\u00ed antagonisty <em>Undecanal<\/em> vystaveny, ztrat\u00ed orientaci a op\u011bt sn\u00ed\u017e\u00ed rychlost.<br>V d\u011blo\u017en\u00edm \u010d\u00edpku je desetkr\u00e1t v\u00edce \u010dichov\u00fdch receptor\u016f ne\u017e v samotn\u00e9m \u010dichov\u00e9m epitelu (10 ... 20 milion\u016f), co\u017e z n\u011bj \u010din\u00ed nejl\u00e9pe st\u0159e\u017een\u00e9 m\u00edsto v lidsk\u00e9m t\u011ble.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Magen-Darm-Trakt\"><\/span>Gastrointestin\u00e1ln\u00ed trakt<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">V tr\u00e1vic\u00edm traktu se nach\u00e1z\u00ed p\u0159ibli\u017en\u011b 15 ... 20 r\u016fzn\u00fdch pachov\u00fdch receptor\u016f. P\u0159i po\u017eit\u00ed nap\u0159. <em>Eugenol<\/em> (h\u0159eb\u00ed\u010dek jako ko\u0159en\u00ed nebo esenci\u00e1ln\u00ed olej), receptor v\u016fn\u011b <em>hOR1D2<\/em> stimulov\u00e1n, na\u010de\u017e <em>Serotonin<\/em> a zvy\u0161uje se peristaltika.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Haut_und_Haare\"><\/span>K\u016f\u017ee a vlasy<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">K\u016f\u017ee je charakterizov\u00e1na bu\u0148kami obsahuj\u00edc\u00edmi keratin (<em>Keratinocyty<\/em>) je udr\u017eov\u00e1na pru\u017en\u00e1 a elastick\u00e1 d\u00edky tomu, \u017ee poko\u017eka (<em>Epidermis<\/em>) zrohovat\u00ed, vytvo\u0159\u00ed se \u0161upiny a jsou nahrazeny \u010derstv\u00fdmi bu\u0148kami rostouc\u00edmi zespodu. V keratinocytech se nach\u00e1z\u00ed v\u00edce ne\u017e 30 pachov\u00fdch receptor\u016f. <em>Sandalore<\/em> je syntetick\u00e1 v\u016fn\u011b santalov\u00e9ho d\u0159eva (syntetick\u00e1, proto\u017ee prav\u00e9 santalov\u00e9 d\u0159evo je velmi drah\u00e9), kter\u00e1 v\u00fdrazn\u011b zvy\u0161uje r\u016fst a pru\u017enost ko\u017en\u00edch bun\u011bk t\u00edm, \u017ee zvy\u0161uje koncentraci v\u00e1pn\u00edku a umo\u017e\u0148uje rychlej\u0161\u00ed hojen\u00ed ran o 40 '%.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zaji\u0161\u0165uje tak\u00e9 <em>Sandalore<\/em> prost\u0159ednictv\u00edm receptor\u016f v bu\u0148k\u00e1ch vlasov\u00fdch ko\u0159\u00ednk\u016f pro 20 % del\u0161\u00ed \u017eivotnost vlas\u016f.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Herz\"><\/span>Srdce<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Receptor v\u016fn\u011b <em>OR51E1<\/em> je v srdci zodpov\u011bdn\u00fd nap\u0159\u00edklad za sn\u00ed\u017een\u00ed srde\u010dn\u00ed frekvence a srde\u010dn\u00edho v\u00fddeje.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Lunge\"><\/span>Pl\u00edce<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">V plic\u00edch je receptor pachu <em>OR2AG1<\/em> se stimulac\u00ed <em>Amylbutyr\u00e1t<\/em> (he\u0159m\u00e1nek \u0159\u00edmsk\u00fd) uvol\u0148uje patologicky sta\u017een\u00e9 bu\u0148ky hladk\u00e9ho svalstva, co\u017e je d\u016fle\u017eit\u00e9 pro astmatiky, alergiky a pacienty s CHOPN.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Prostata\"><\/span>Prostata<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Receptor v\u016fn\u011b <em>hOR51E2<\/em> je ve velk\u00e9m mno\u017estv\u00ed exprimov\u00e1n v bu\u0148k\u00e1ch karcinomu prostaty a slou\u017e\u00ed jako n\u00e1dorov\u00fd marker. <em>\u03b2-ionon<\/em> (fialov\u00e1 v\u016fn\u011b) sni\u017euje m\u00edru proliferace (rychlost r\u016fstu). V sou\u010dasn\u00e9 dob\u011b v\u0161ak nen\u00ed zn\u00e1m \u017e\u00e1dn\u00fd zp\u016fsob, jak dopravit molekuly v\u016fn\u011b na m\u00edsto p\u016fsoben\u00ed, a to ani prost\u0159ednictv\u00edm krve. (<a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(18)93050-4\/fulltext\" target=\"_blank\" rel=\"noreferrer noopener\">Zdroj:<\/a>)<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Blase\"><\/span>Bublina<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">U rakoviny mo\u010dov\u00e9ho m\u011bch\u00fd\u0159e je \u010dichov\u00fd receptor <em>OR10H1<\/em> vyj\u00e1d\u0159eno. Stimulace pomoc\u00ed <em>Sandranol<\/em> (<em>Santalol<\/em>), p\u0159\u00edrodn\u00ed santalov\u00fd olej, brzd\u00ed a omezuje r\u016fst n\u00e1dor\u016f. Test mo\u010di umo\u017e\u0148uje vyvodit z\u00e1v\u011bry o tom, zda se jedn\u00e1 o rakovinu mo\u010dov\u00e9ho m\u011bch\u00fd\u0159e \u010di nikoliv, proto\u017ee odum\u0159el\u00e9 bu\u0148ky z vnit\u0159n\u00ed st\u011bny mo\u010dov\u00e9ho m\u011bch\u00fd\u0159e se vyplavuj\u00ed mo\u010d\u00ed. (<a href=\"https:\/\/www.frontiersin.org\/journals\/physiology\/articles\/10.3389\/fphys.2018.00456\/full\" target=\"_blank\" rel=\"noreferrer noopener\">Zdroj:<\/a>)<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Kolon\"><\/span>St\u0159eva<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Receptor v\u016fn\u011b <em>OR51B4<\/em> se uvol\u0148uje v p\u0159\u00edpad\u011b karcinomu tlust\u00e9ho st\u0159eva. Bu\u0148ky karcinomu tlust\u00e9ho st\u0159eva (<em>HCT116<\/em>) reaguj\u00ed na v\u016fni <em>Troenan<\/em> (privet), kter\u00fd v\u00fdznamn\u011b inhibuje r\u016fst n\u00e1doru t\u00edm, \u017ee m\u011bn\u00ed morfologii bun\u011bk rakoviny tlust\u00e9ho st\u0159eva.<br>(<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28273117\/\" target=\"_blank\" rel=\"noreferrer noopener\">Zdroj:<\/a>)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Liste_aller_Olfaktorischen_Rezeptoren\"><\/span>Seznam v\u0161ech \u010dichov\u00fdch receptor\u016f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">K dispozici je n\u00e1sleduj\u00edc\u00ed (v\u00fd\u0148atkov\u00fd) seznam v\u0161ech lidsk\u00fdch \u010dichov\u00fdch receptor\u016f, v\u010detn\u011b v\u0161ech v\u011bdeck\u00fdch \u00fadaj\u016f. <a href=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/Olfactory.xlsx\">zde<\/a> je k dispozici ke sta\u017een\u00ed ve form\u00e1tu Excel.<br>Data poch\u00e1zej\u00ed z <a href=\"https:\/\/www.proteinatlas.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">Atlas lidsk\u00fdch protein\u016f<\/a>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/Olfactory.xlsx\"><img decoding=\"async\" width=\"1024\" height=\"337\" src=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-11-1024x337.png\" alt=\"\" class=\"wp-image-9713\" srcset=\"https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-11-1024x337.png 1024w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-11-300x99.png 300w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-11-768x253.png 768w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-11-1536x506.png 1536w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-11-2048x674.png 2048w, https:\/\/csiag.eu\/wp-content\/uploads\/2025\/03\/image-11-18x6.png 18w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Worauf_basiert_die_antibakterielle_antivirale_Wirkung\"><\/span>Na \u010dem je zalo\u017een antibakteri\u00e1ln\u00ed\/antivirov\u00fd \u00fa\u010dinek?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Antibakteri\u00e1ln\u00ed nebo antivirov\u00fd \u00fa\u010dinek \u00e9terick\u00fdch olej\u016f je zalo\u017een na p\u0159\u00edm\u00e9m p\u016fsoben\u00ed molekul oleje na p\u0159\u00edslu\u0161nou bakterii nebo virus a tak\u00e9 na p\u016fsoben\u00ed na imunomodula\u010dn\u00ed nebo hormon\u00e1ln\u00ed regula\u010dn\u00ed okruhy.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Bakterien\"><\/span>Bakterie<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Bakterie se d\u011bl\u00ed na dva typy: grampozitivn\u00ed a gramnegativn\u00ed. Rozli\u0161uj\u00ed se mikroskopicky pomoc\u00ed tzv. Gramova barven\u00ed, pojmenovan\u00e9ho podle d\u00e1nsk\u00e9ho bakteriologa a l\u00e9ka\u0159e. <em>Hans Christian Gram<\/em> (1853-1938).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Alkalick\u00e9 barvivo <em>K\u0159i\u0161\u0165\u00e1lov\u011b fialov\u00e1<\/em> barv\u00ed grampozitivn\u00ed bakterie fialov\u011b, zat\u00edmco v protibarv\u011b s <em>Fuchsin<\/em> nebo <em>\u0160afr\u00e1n<\/em> pouze gramnegativn\u00ed bakterie m\u011bn\u00ed barvu na \u010dervenou nebo r\u016f\u017eovou.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">To se odr\u00e1\u017e\u00ed ve struktu\u0159e tlust\u00e9ho <em>Peptidoglykanov\u00e1 vrstva<\/em> grampozitivn\u00edch bakteri\u00ed a tenkou bun\u011b\u010dnou st\u011bnu a vn\u011bj\u0161\u00ed membr\u00e1nu gramnegativn\u00edch bakteri\u00ed.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Molekuly esenci\u00e1ln\u00edch olej\u016f p\u0159\u00edmo napadaj\u00ed tyto slo\u017eky bakteri\u00ed, ni\u010d\u00ed jejich obal a inhibuj\u00ed jejich enzymy, co\u017e vede k antibakteri\u00e1ln\u00edmu \u00fa\u010dinku.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Viren\"><\/span>Viry<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Viry se tak\u00e9 d\u011bl\u00ed na dva typy, na ty s obalem (nap\u0159. <em>Ch\u0159ipka<\/em>, <em>HIV<\/em>) a bez obalu (nap\u0159. <em>Adeno<\/em>- a <em>Noroviry<\/em>).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Genetick\u00fd materi\u00e1l (<em>DNA<\/em> nebo <em>RNA<\/em>) vir\u016f je v <em>Kapsida<\/em> kter\u00e1 se skl\u00e1d\u00e1 z b\u00edlkovinn\u00fdch jednotek, a <em>Capsomeres<\/em> existuje.<br>N\u011bkter\u00e9 viry maj\u00ed tak\u00e9 lipidovou membr\u00e1nu, kterou odstra\u0148uj\u00ed z hostitelsk\u00e9 bu\u0148ky, jakmile ji opust\u00ed, aby se pomoc\u00ed sv\u00fdch virov\u00fdch protein\u016f (glykoprotein\u016f) zabudovan\u00fdch do t\u00e9to membr\u00e1ny mohly p\u0159ipojit k jin\u00fdm hostitelsk\u00fdm bu\u0148k\u00e1m.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">I zde molekuly \u00e9terick\u00fdch olej\u016f p\u0159\u00edmo \u00fato\u010d\u00ed na virus a \u010din\u00ed ho ne\u0161kodn\u00fdm.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Wie_verstecken_sich_Viren\"><\/span>Jak se viry skr\u00fdvaj\u00ed?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">V ur\u010dit\u00e9m smyslu se viry skr\u00fdvaj\u00ed v t\u011blesn\u00fdch bu\u0148k\u00e1ch, kdy\u017e po ur\u010ditou dobu produkuj\u00ed jen m\u00e1lo vir\u016f (n\u00e1lo\u017e) nebo je v\u016fbec neprodukuj\u00ed, p\u0159\u00edpadn\u011b se vyh\u00fdbaj\u00ed rozpozn\u00e1n\u00ed imunitn\u00edm syst\u00e9mem prost\u0159ednictv\u00edm mutac\u00ed v rychl\u00e9m sledu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Dal\u0161\u00ed metodou je jejich ukryt\u00ed nap\u0159\u00edklad v ledvin\u00e1ch, o\u010d\u00edch nebo mozku nebo jejich prost\u00e9 potla\u010den\u00ed. <em>Prezentace MHC-I<\/em> nebo blokov\u00e1n\u00ed <em>Interferonov\u00e9 sign\u00e1ln\u00ed dr\u00e1hy<\/em>.<br>Ob\u011b slou\u017e\u00ed k rozpozn\u00e1n\u00ed exogenn\u00edch peptid\u016f (aminokyselin s kr\u00e1tk\u00fdm \u0159et\u011bzcem na rozd\u00edl od b\u00edlkovin s dlouh\u00fdm \u0159et\u011bzcem) a n\u00e1sledn\u011b iniciuj\u00ed vznik peptid\u016f. <em>Apopt\u00f3za<\/em> (bun\u011b\u010dn\u00e1 smrt),<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Signalwege\"><\/span>Sign\u00e1ln\u00ed dr\u00e1hy<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Krom\u011b p\u0159\u00edm\u00e9ho \u00fatoku p\u016fsob\u00ed molekuly \u00e9terick\u00fdch olej\u016f tak\u00e9 jako sign\u00e1ln\u00ed \u010dinidla, proto\u017ee prost\u0159ednictv\u00edm bun\u011b\u010dn\u00fdch receptor\u016f spou\u0161t\u011bj\u00ed procesy, kter\u00e9 maj\u00ed imunomodula\u010dn\u00ed \u00fa\u010dinky a\/nebo uv\u00e1d\u011bj\u00ed do pohybu hormon\u00e1ln\u00ed regula\u010dn\u00ed mechanismy.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>Pozn\u00e1mka<\/strong><br>V\u00fdzkum neust\u00e1le pokra\u010duje. V\u00fd\u0161e uveden\u00fd \u010dl\u00e1nek si ne\u010din\u00ed n\u00e1rok na \u00faplnost. Pokud jsou \u010dten\u00e1\u0159i zn\u00e1my n\u011bjak\u00e9 skute\u010dnosti v tomto ohledu s odkazy, kter\u00e9 zde nebyly uvedeny, pros\u00edm, aby mi dali v\u011bd\u011bt. <a href=\"mailto:\/\/info@csiag.de\" target=\"_blank\" rel=\"noopener\">N\u00e1pov\u011bda<\/a>.<\/p>\n<\/blockquote>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Quellenangaben\"><\/span>Odkazy<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Dal\u0161\u00ed studie na toto t\u00e9ma najdete mimo jin\u00e9 pod n\u00e1sleduj\u00edc\u00edmi odkazy:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2024-10-04<\/strong> - <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39365517\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u010cichov\u00e9 receptory a n\u00e1dorov\u00e9 bujen\u00ed: d\u016fsledky pro diagnostiku a c\u00edlenou terapii<\/a><br>(Shrnut\u00ed - \u00fapln\u00e9 zn\u011bn\u00ed s n\u00e1klady - 54 odkaz\u016f)<br><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Tang+Y&amp;cauthor_id=39365517\" target=\"_blank\" rel=\"noopener\">Yi Tang<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39365517\/#full-view-equal-contrib-explanation\" target=\"_blank\" rel=\"noopener\">#<\/a>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39365517\/#full-view-affiliation-1\" target=\"_blank\" rel=\"noopener\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Tian+Y&amp;cauthor_id=39365517\" target=\"_blank\" rel=\"noopener\">Ye Tian<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39365517\/#full-view-equal-contrib-explanation\" target=\"_blank\" rel=\"noopener\">#<\/a>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39365517\/#full-view-affiliation-2\" target=\"_blank\" rel=\"noopener\">2<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Zhang+CX&amp;cauthor_id=39365517\" target=\"_blank\" rel=\"noopener\">Chun-Xia Zhang<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39365517\/#full-view-affiliation-1\" target=\"_blank\" rel=\"noopener\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Wang+GT&amp;cauthor_id=39365517\" target=\"_blank\" rel=\"noopener\">Guo-Tai Wang<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39365517\/#full-view-affiliation-3\" target=\"_blank\" rel=\"noopener\">3<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2021-02-05<\/strong> - <a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-021-00962-0\" target=\"_blank\" rel=\"noreferrer noopener\">Muta\u010dn\u00ed krajina lidsk\u00fdch \u010dichov\u00fdch receptor\u016f sp\u0159a\u017een\u00fdch s G proteiny<\/a><br>(Cel\u00fd text - 66 odkaz\u016f)<br><a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-021-00962-0#auth-Ram_n_Cierco-Jimenez-Aff1-Aff2\" target=\"_blank\" rel=\"noopener\">Ram\u00f3n Cierco Jimenez<\/a>,&nbsp;<a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-021-00962-0#auth-Nil-Casajuana_Martin-Aff1\" target=\"_blank\" rel=\"noopener\">Nile Casajuana-Martin<\/a>,&nbsp;<a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-021-00962-0#auth-Adri_n-Garc_a_Recio-Aff1\" target=\"_blank\" rel=\"noopener\">Adri\u00e1n Garc\u00eda-Recio<\/a>,&nbsp;<a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-021-00962-0#auth-Lidia-Alc_ntara-Aff1\" target=\"_blank\" rel=\"noopener\">Lidia Alc\u00e1ntara<\/a>,&nbsp;<a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-021-00962-0#auth-Leonardo-Pardo-Aff1\" target=\"_blank\" rel=\"noopener\">Leonardo Pardo<\/a>,&nbsp;<a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-021-00962-0#auth-Mercedes-Campillo-Aff1\" target=\"_blank\" rel=\"noopener\">Mercedes Campillo<\/a>&nbsp;&amp;&nbsp;<a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-021-00962-0#auth-Angel-Gonzalez-Aff1\" target=\"_blank\" rel=\"noopener\">Angel Gonzalez<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2018-11-30<\/strong> - <a href=\"https:\/\/www.nature.com\/articles\/s41573-018-0002-3\" target=\"_blank\" rel=\"noreferrer noopener\">Terapeutick\u00fd potenci\u00e1l ektopick\u00fdch \u010dichov\u00fdch a chu\u0165ov\u00fdch receptor\u016f<\/a><br>(Shrnut\u00ed - \u00fapln\u00e9 zn\u011bn\u00ed s n\u00e1klady - 317 odkaz\u016f)<br><a href=\"https:\/\/www.nature.com\/articles\/s41573-018-0002-3#auth-Sung_Joon-Lee-Aff1\" target=\"_blank\" rel=\"noopener\">Sung-Joon Lee<\/a>,&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/s41573-018-0002-3#auth-Inge-Depoortere-Aff2\" target=\"_blank\" rel=\"noopener\">Inge Depoortere<\/a>&nbsp;&amp;&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/s41573-018-0002-3#auth-Hanns-Hatt-Aff3\" target=\"_blank\" rel=\"noopener\">Hanns Hatt<\/a>&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2018-06.13<\/strong> - <a href=\"https:\/\/journals.physiology.org\/doi\/full\/10.1152\/physrev.00013.2017?rfr_dat=cr_pub++0pubmed&amp;url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org\" target=\"_blank\" rel=\"noreferrer noopener\">Lidsk\u00e9 \u010dichov\u00e9 receptory: nov\u00e9 bun\u011b\u010dn\u00e9 funkce mimo nos<\/a><br>(Cel\u00fd text - 212 odkaz\u016f)<br><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ma%C3%9Fberg+D&amp;cauthor_id=29897292\" target=\"_blank\" rel=\"noopener\">D\u00e9sir\u00e9e Ma\u00dfberg<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29897292\/#full-view-affiliation-1\" target=\"_blank\" rel=\"noopener\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Hatt+H&amp;cauthor_id=29897292\" target=\"_blank\" rel=\"noopener\">Hanns Hatt<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29897292\/#full-view-affiliation-1\" target=\"_blank\" rel=\"noopener\">1<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2009-10-30<\/strong> - <a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)38109-6\/fulltext\" target=\"_blank\" rel=\"noreferrer noopener\">Dvoj\u00ed p\u016fsoben\u00ed odorant\u016f na \u010dichov\u00e9 a jadern\u00e9 hormon\u00e1ln\u00ed receptory<\/a><br>(Cel\u00fd text - 74 odkaz\u016f)<br><a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)38109-6\/fulltext#\" target=\"_blank\" rel=\"noopener\">Horst Pick<\/a><sup><a>\u2021<\/a>,<a>1<\/a><\/sup>&nbsp;\u2219&nbsp;<a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)38109-6\/fulltext#\" target=\"_blank\" rel=\"noopener\">Sylvain Etter<\/a><sup><a>\u2021<\/a>,<a>1<\/a><\/sup>&nbsp;\u2219&nbsp;<a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)38109-6\/fulltext#\" target=\"_blank\" rel=\"noopener\">Olivia Baud<\/a><sup><a>\u2021<\/a><\/sup>&nbsp;\u2219&nbsp;<a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)38109-6\/fulltext#\" target=\"_blank\" rel=\"noopener\">Ralf Schmauder<\/a><sup><a>\u2021<\/a><\/sup>&nbsp;\u2219&nbsp;<a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)38109-6\/fulltext#\" target=\"_blank\" rel=\"noopener\">Lorenza Bordoli<\/a><sup><a>\u00a7<\/a><\/sup>&nbsp;\u2219&nbsp;<a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)38109-6\/fulltext#\" target=\"_blank\" rel=\"noopener\">Torsten Schwede<\/a><sup><a>\u00a7<\/a><\/sup>&nbsp;\u2219&nbsp;<a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)38109-6\/fulltext#\" target=\"_blank\" rel=\"noopener\">Horst Vogel<\/a><sup><a>\u2021<\/a><\/sup>&nbsp;<a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(20)38109-6\/fulltext\" target=\"_blank\" rel=\"noreferrer noopener\"><br><\/a><\/p>","protected":false},"excerpt":{"rendered":"<p><span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Doba \u010dten\u00ed<\/span> <span class=\"rt-time\"> 12<\/span> <span class=\"rt-label rt-postfix\">minuty<\/span><\/span>Pro\u010d esenci\u00e1ln\u00ed oleje funguj\u00ed? Tato ot\u00e1zka je opr\u00e1vn\u011bn\u00e1 a odpov\u011b\u010f na ni je nesm\u00edrn\u011b hlubok\u00e1 a ne\u010dekan\u011b vzru\u0161uj\u00edc\u00ed. V\u016fn\u011b - ka\u017ed\u00fd asi zn\u00e1 vonn\u00e9 lampy a vonn\u00e9 sv\u00ed\u010dky, jejich\u017e v\u016fn\u011b nen\u00ed v\u017edy vn\u00edm\u00e1na jako p\u0159\u00edjemn\u00e1, ale \u010dasto zp\u016fsobuje bolesti hlavy, nep\u0159\u00edjemn\u00e9 pocity a dokonce nevolnost, zejm\u00e9na v p\u0159\u00edpad\u011b syntetick\u00fdch vonn\u00fdch olej\u016f. V\u016fn\u011b sv\u00e1d\u011bj\u00ed, a to nejen v podob\u011b \u017eensk\u00e9ho parf\u00e9mu, ale i v podob\u011b...&nbsp;<a href=\"https:\/\/csiag.eu\/cs\/blog\/2025\/03\/12\/aetherische-oele-warum-wirken-sie\/\" rel=\"bookmark\">\u010c\u00edst d\u00e1le \"<span class=\"screen-reader-text\">Esenci\u00e1ln\u00ed oleje - pro\u010d funguj\u00ed?<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"","neve_meta_content_width":0,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[3401,1078,354],"tags":[4614,4599,4557,3905,3923,3906,4639,3094,4623,650,4640,4590,4642,4643,1495,4625,3117,4567,4593,4587,4566,4655,4654,4671,4548,4636,3945,691,4396,4550,4551,3903,4549,3920,4633,4619,4620,4641,4615,4595,4621,4627,4610,4679,4624,2825,4685,4676,4559,4681,4584,4578,4674,4616,4682,1446,140,4582,4591,4634,4555,4556,4658,4612,4644,1427,4596,4592,4652,1751,3457,4573,4564,4565,143,3747,4628,4588,139,3932,4675,4680,4609,4677,4645,24,3446,4602,4613,3069,141,4647,4646,3897,4631,3089,3090,4630,4314,4558,2814,4572,4618,4629,4560,3732,1131,4568,4561,4601,4622,2104,3404,4649,4589,4626,4552,4632,4600,4684,4580,4579,4583,4554,4563,4575,4553,4576,4585,4367,4650,4683,4574,4653,4656,4586,4571,4547,4672,3745,3898,4598,4569,4570,4597,4603,4605,4604,4608,4607,4606,3364,4673,1101,3935,4350,4594,2108,4546,3736,3737,4617,3289,42,4686,4651,4648,4611,43],"class_list":["post-9568","post","type-post","status-publish","format-standard","hentry","category-aetherische-oele","category-medizin","category-medizin-gesundheit","tag-abc-pflaster","tag-aktionspotenzial","tag-analgetika","tag-antibakteriell","tag-antimykotisch","tag-antiviral","tag-atemwegsmuskulatur","tag-aetherische-oele","tag-ausschuettung","tag-bakterien","tag-bauspeicheldruese","tag-beurteilung","tag-blase","tag-blut","tag-blut-hirn-schranke","tag-blutgefaess","tag-blutgefaesse","tag-capsaicin","tag-chemische-reize","tag-chemorezeptor","tag-chili","tag-deoxyribonucleic-acid","tag-deoxyribonukleinsaeure","tag-diagnostik","tag-diagnostisch","tag-dickdarm","tag-diffusor","tag-dna","tag-duft","tag-duftkerze","tag-duftkerzen","tag-duftlampe","tag-duftlampen","tag-duftoele","tag-duftrezeptor","tag-endorphine","tag-enkephaline","tag-enterochromaffine-zellen","tag-entzuendungsreiz","tag-erfrierung","tag-erotonin","tag-eugenol","tag-eukalytol","tag-expression","tag-exprimieren","tag-forschung","tag-forschungsergebnisse","tag-fpkm","tag-fressfeinde","tag-genexpression","tag-geschmack","tag-geschmacksknospen","tag-gewebeprobe","tag-gewebeschaedigung","tag-hanns-hatt","tag-haut","tag-herz","tag-herzhaft","tag-hitze","tag-hoden","tag-hpnotika","tag-hypnotikum","tag-informationsstrang","tag-ingwer-oel","tag-inhalatorisch","tag-ionen","tag-ionenkanal","tag-kaelte","tag-kommunikation","tag-konzentration","tag-kopfschmerz","tag-kortex","tag-lavendel","tag-lavendel-duft","tag-leber","tag-linalool","tag-linalylacetat","tag-lokalisierung","tag-lunge","tag-magen-darm-trakt","tag-mammakarzinom","tag-marker","tag-menthol","tag-metrik","tag-molekuele","tag-mrna","tag-nase","tag-negativ","tag-neleken-oel","tag-nervenzellen","tag-niere","tag-nucleus","tag-nukleus","tag-olfaktorisch","tag-olfatorischer-rezeptor","tag-opiat","tag-opiate","tag-or","tag-palliativ","tag-palliativmedizin","tag-pankreas","tag-parietallappen","tag-pepperoni","tag-perkutan","tag-pfefferminze","tag-pflanze","tag-pflanzen","tag-piperin","tag-plize","tag-positiv","tag-prostaglandine","tag-protein","tag-proteine","tag-prozess","tag-qualitativ","tag-rezeptorreiz","tag-riechen","tag-riechrezeptor","tag-ruhepotenzial","tag-ruhr-universitaet-bochum","tag-salzig","tag-sauer","tag-scharf","tag-schlafmittel","tag-schmecken","tag-schmerz","tag-schmerzmittel","tag-schmerzreiz","tag-schmerzrezeptor","tag-schwarzer-pfeffer","tag-semi-permeable-membran","tag-sinnesphysiologie","tag-somatosensorisch","tag-stoffaustausch","tag-synthes","tag-temperaturrezeptor","tag-thalamus","tag-therapeutisch","tag-therapie","tag-thymol","tag-topisch","tag-transient-receptor-potential","tag-trigeminus","tag-trigeminus-nerv","tag-trp","tag-trpa1","tag-trpm8","tag-trpv1","tag-trpv2","tag-trpv3","tag-trpv4","tag-tumor","tag-tumoraktivitaet","tag-uebelkeit","tag-unwohlsein","tag-veraetzung","tag-verbrennung","tag-viren","tag-wirken","tag-wirkstoff","tag-wirkstoffe","tag-wrnfunktion","tag-zelle","tag-zellkern","tag-zelllinie","tag-zellmembran","tag-zellulaer","tag-zimt-oel","tag-zytoplasma"],"modified_by":"Achim Goerner","_links":{"self":[{"href":"https:\/\/csiag.eu\/cs\/wp-json\/wp\/v2\/posts\/9568","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/csiag.eu\/cs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csiag.eu\/cs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csiag.eu\/cs\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/csiag.eu\/cs\/wp-json\/wp\/v2\/comments?post=9568"}],"version-history":[{"count":0,"href":"https:\/\/csiag.eu\/cs\/wp-json\/wp\/v2\/posts\/9568\/revisions"}],"wp:attachment":[{"href":"https:\/\/csiag.eu\/cs\/wp-json\/wp\/v2\/media?parent=9568"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csiag.eu\/cs\/wp-json\/wp\/v2\/categories?post=9568"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csiag.eu\/cs\/wp-json\/wp\/v2\/tags?post=9568"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}