{"id":12205,"date":"2026-01-11T13:18:25","date_gmt":"2026-01-11T13:18:25","guid":{"rendered":"https:\/\/csiag.eu\/?p=12205"},"modified":"2026-04-02T13:32:13","modified_gmt":"2026-04-02T13:32:13","slug":"huaier-sene-hroniskam-slimibam","status":"publish","type":"post","link":"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/","title":{"rendered":"Huaier s\u0113ne hronisk\u0101m slim\u012bb\u0101m"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_87_1 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Satura r\u0101d\u012bt\u0101js<\/p>\n<span class=\"ez-toc-title-toggle\"><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Autoimmunerkrankungen\" >Autoim\u016bn\u0101s slim\u012bbas<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Immunthrombozytopenie_ITP\" >Im\u016bn\u0101 trombocitop\u0113nija (ITP)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Rheumatoide_Arthritis_RA\" >Reimato\u012bdais artr\u012bts (RA)<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Chronisch_entzundliche_Erkrankungen\" >Hroniskas iekaisuma slim\u012bbas<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Colitis_ulcerosa_und_entzundliche_Darmerkrankungen_IBD\" >\u010c\u016blainais kol\u012bts un zarnu iekaisuma slim\u012bba (IBD)<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Differenzierung_Colitis_ulcerosa_vs_Morbus_Crohn\" >\u010c\u016blain\u0101 kol\u012bta un Krona slim\u012bbas diferenci\u0101cija<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Lokalisation\" >Lokaliz\u0101cija<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Colitis_ulcerosa_CU\" >\u010c\u016blainais kol\u012bts (\u010cK)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Morbus_Crohn_MC\" >Krona slim\u012bba (MC)<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Entzundungstiefe\" >Iekaisuma dzi\u013cums<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#UC\" >UC<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#MC\" >MC<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Allergische_Erkrankungen_Asthma_Allergien\" >Aler\u0123iskas slim\u012bbas (astma, aler\u0123ijas).<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Kardiovaskulare_Erkrankungen\" >Sirds un asinsvadu slim\u012bbas<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Neurodegenerative_Erkrankungen_%E2%80%93_Parkinson\" >Neirode\u0123enerat\u012bvas slim\u012bbas - Parkinsona slim\u012bba<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Postinfektiose_Syndrome\" >P\u0113cinfekcijas sindromi<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Mogliche_Rolle_nach_mRNA-Vakzinationen\" >Iesp\u0113jam\u0101 loma p\u0113c mRNS vakcin\u0101cijas<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Chronische_Lebererkrankungen_%E2%80%93_Hepatozellulares_Karzinom_HCC\" >Hroniskas aknu slim\u012bbas - Hepatocelul\u0101r\u0101 karcinoma (HCC)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Das_universelle_Wirkprinzip_von_Huaier\" >Huaier univers\u0101lais darb\u012bbas princips<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Signalweg-Architektur\" >Sign\u0101la ce\u013ca arhitekt\u016bra<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Dosierung_bei_chronischen_Erkrankungen\" >Devas hronisk\u0101m slim\u012bb\u0101m<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Sicherheit_und_Vertraglichkeit\" >Dro\u0161\u012bba un sader\u012bba<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/#Anmerkung\" >Piez\u012bme<\/a><\/li><\/ul><\/nav><\/div>\n<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Las\u012b\u0161anas laiks<\/span> <span class=\"rt-time\"> 5<\/span> <span class=\"rt-label rt-postfix\">protokols<\/span><\/span>\n<p class=\"wp-block-paragraph\">Huaier s\u0113ne hronisku slim\u012bbu \u0101rst\u0113\u0161anai - zin\u0101tniskie p\u0113t\u012bjumi, indik\u0101cijas un darb\u012bbas meh\u0101nismi<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pa\u0161laik veikto p\u0113t\u012bjumu dati liecina, ka Huaier ir daudzsolo\u0161s ar\u012b autoim\u016bno slim\u012bbu, hronisku iekaisumu, sirds un asinsvadu slim\u012bbu, neirode\u0123enerat\u012bvu trauc\u0113jumu un postinfekcijas sindromu, piem\u0113ram, ME\/CFS vai postvaku sindroma, \u0101rst\u0113\u0161an\u0101.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Huaier piem\u012bt pla\u0161a spektra regul\u0113jo\u0161a iedarb\u012bba uz da\u017e\u0101diem iedzimt\u0101s un adapt\u012bv\u0101s im\u016bnsist\u0113mas komponentiem, tostarp makrof\u0101giem, dendr\u012bt\u0161\u016bn\u0101m, dabiskaj\u0101m \u0161\u016bn\u0101m-zin\u0101tniec\u0113m, T un B limfoc\u012btiem.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Port\u0101ls <a href=\"https:\/\/aditum.org\/journals\/international-journal-of-medical-case-reports-and-medical-research\/archive\/967\" target=\"_blank\" rel=\"noreferrer noopener\">Tanakas p\u0113t\u012bjums<\/a> ir pamats \u0161\u0101diem apgalvojumiem. Ieteikumi par devu lieto\u0161anu saist\u012bb\u0101 ar v\u0113\u017ea terapiju ir atrodami <a href=\"https:\/\/csiag.eu\/lv\/huaier-senes-veza-terapija\/#Dosierungsempfehlung\" target=\"_blank\" rel=\"noreferrer noopener\">\u0161eit<\/a>. P\u0113t\u012bjum\u0101 izmantoto 32% polisahar\u012bdu granulu pieg\u0101des avots ir <a href=\"https:\/\/nutrimentas-shop.de\/products\/vitalpilz-huaier-trametes-robiniophila-fur-wissenschaftliche-zwecke\" target=\"_blank\" rel=\"noreferrer noopener\">\u0161eit<\/a>.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Die therapeutische Anwendung basiert auf den in der Tanaka-Studie bestimmten Wirkstoffgehalten.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Viele Anbieter, selbst apothekenpflichtige Produkte erreichen diesen Standard meist nicht und bieten nur bis 30% Polysaccharide, noch seltener sind Daten unabh\u00e4ngiger Analyse-Labore zug\u00e4nglich.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Die o.g. Bezugsquelle (<a href=\"https:\/\/nutrimentas-shop.de\/products\/vitalpilz-huaier-trametes-robiniophila-fur-wissenschaftliche-zwecke\" target=\"_blank\" rel=\"noreferrer noopener\">Saite<\/a>) weist s\u00e4mtliche Daten per Link unter der Produktbeschreibung nach und ist damit, Stand 04.2026, m.W. einzigartig.<\/p>\n<\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">Ir identific\u0113tas devi\u0146as galven\u0101s Huaier s\u0113nes akt\u012bv\u0101s vielas, kas iedarbojas uz vair\u0101kiem signaliz\u0101cijas ce\u013ciem:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>TP-1<\/strong> (polisahar\u012bds, 2300 kDa*)<\/li>\n\n\n\n<li><strong>HP-1<\/strong> (polisahar\u012bds, 30 kDa)<\/li>\n\n\n\n<li><strong>PS-T<\/strong> (Polisahar\u012bdu-prote\u012bnu komplekss: 40% polisahar\u012bdu + 10% aminosk\u0101bju)<\/li>\n\n\n\n<li><strong>Rut\u012bns<\/strong> (flavono\u012bds)<\/li>\n\n\n\n<li><strong>Kaempferols<\/strong> (flavono\u012bds)<\/li>\n\n\n\n<li><strong>Geniste\u012bns<\/strong> (Izoflavono\u012bds)<\/li>\n\n\n\n<li><strong>Glikuma sk\u0101be<\/strong> (cukurs-sk\u0101be)<\/li>\n\n\n\n<li><strong>Daucosterol<\/strong> (Sterols)<\/li>\n\n\n\n<li><strong>W-NTRP<\/strong> (\u016bden\u012b \u0161\u0137\u012bsto\u0161s polisahar\u012bds)<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">*kDa izmanto, lai nor\u0101d\u012btu molekulu, \u012bpa\u0161i olbaltumvielu, masu. Daltona m\u0113rvien\u012bba (Da) ir oglek\u013ca izotopa 12C masas divpadsmit\u0101 da\u013ca un ir 1,66053906660(50) - 10-\u00b2\u2077 kg. kDa ir praktiski identiska kg\/mol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Autoimmunerkrankungen\"><\/span>Autoim\u016bn\u0101s slim\u012bbas<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Immunthrombozytopenie_ITP\"><\/span>Im\u016bn\u0101 trombocitop\u0113nija (ITP)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">ir autoim\u016bna slim\u012bba ar \u013coti samazin\u0101tu tromboc\u012btu skaitu, ko parasti \u0101rst\u0113 ar kortikostero\u012bdiem \/ im\u016bnsupresantiem (ar masveida blakuspar\u0101d\u012bb\u0101m).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Autoim\u016bn\u0101s reakcijas pret tromboc\u012btiem d\u0113\u013c slim\u012bbas skartajiem pacientiem ir iev\u0113rojami samazin\u0101ts \u0161o \u0161\u016bnu skaits, kas ir svar\u012bgas asins rec\u0113\u0161anas proces\u0101.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u016adenisk\u0101 huai ekstrakta lieto\u0161ana im\u016bn\u0101s trombocitop\u0113nijas gad\u012bjum\u0101 tika p\u0113t\u012bta ar <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34450221\/\" target=\"_blank\" rel=\"noreferrer noopener\">In vitro p\u0113t\u012bjums<\/a> raksturo k\u0101 veiksm\u012bgu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Darb\u012bbas meh\u0101nisms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Regul\u0113 autoim\u016bno reakciju (nevis to nom\u0101c).<\/li>\n\n\n\n<li>Modul\u0113 B limfoc\u012btus (ra\u017eo boj\u0101t\u0101s antivielas).<\/li>\n\n\n\n<li>normaliz\u0113 tromboc\u012btu veido\u0161anos<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Rheumatoide_Arthritis_RA\"><\/span>Reimato\u012bdais artr\u012bts (RA)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Reimato\u012bdais artr\u012bts ir nezin\u0101mas izcelsmes hroniska iekaisuma autoim\u016bna slim\u012bba. T\u0101 galvenok\u0101rt skar loc\u012btavas, bet ar\u012b org\u0101nus. Tai rakstur\u012bga ar\u012b intermit\u0113jo\u0161a norise. To izraisa nepareizi virz\u012btas im\u016bnsist\u0113mas uzbrukums sinovi\u0101lajai membr\u0101nai (sinovi\u0101lajai g\u013cot\u0101dai). Tas izraisa iekaisuma reakciju, ko pavada, piem\u0113ram, s\u0101pes, piet\u016bkums un st\u012bvums. Att\u012bst\u012bt\u0101 stadij\u0101 var rasties neatgriezeniski loc\u012btavu boj\u0101jumi un deform\u0101cijas.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Darb\u012bbas meh\u0101nisms RA gad\u012bjum\u0101:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Inhib\u0113 proiekaisuma citok\u012bnus (TNF-\u03b1, IL-6, IL-1\u03b2).<\/li>\n\n\n\n<li>Samazina autoantivielu veido\u0161anos<\/li>\n\n\n\n<li>Veicina regulat\u012bvo T \u0161\u016bnu (Tregs = im\u016bnsist\u0113mas dabisk\u0101 \u201ebremze\u201c) veido\u0161anos.<\/li>\n\n\n\n<li>Samazina vai p\u0101rtrauc Th17 diferenci\u0101ciju (proiekaisuma).<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Huaier regul\u0113 novirz\u012bto im\u016bnsist\u0113mas reakciju, lai t\u0101 atkal b\u016btu l\u012bdzsvar\u0101.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Chronisch_entzundliche_Erkrankungen\"><\/span>Hroniskas iekaisuma slim\u012bbas<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Colitis_ulcerosa_und_entzundliche_Darmerkrankungen_IBD\"><\/span>\u010c\u016blainais kol\u012bts un zarnu iekaisuma slim\u012bba (IBD)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Attiec\u012bb\u0101 uz Trametes robiniophila \u016bdens ekstrakta izmanto\u0161anu zarnu iekaisuma slim\u012bbas \u010d\u016blain\u0101 kol\u012bta \u0101rst\u0113\u0161anai p\u0113t\u012bjums liecina, ka <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5464840\/\" target=\"_blank\" rel=\"noreferrer noopener\">Huaier \u016bdens ekstrakts pasarg\u0101 peles no dekstr\u0101na sulf\u0101ta n\u0101trija s\u0101ls izrais\u012bta eksperiment\u0101la kol\u012bta, inhib\u0113jot NLRP3 inflam\u0101somasomas aktiv\u0101ciju<\/a> Wang e.a. uzr\u0101d\u012bja daudzsolo\u0161us rezult\u0101tus. Zin\u0101tnieki izmantoja ar dekstr\u0101na n\u0101trija sulf\u0101tu \u0137\u012bmiski izrais\u012btu zarnu slim\u012bbu pel\u0113m.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Huaier iev\u0113rojami mazin\u0101ja zarnu iekaisumu, par ko liecina vair\u0101ku citok\u012bnu, tostarp TNF-\u03b1, IL-6, IFN-\u03b3 un IL-1\u03b2, samazin\u0101\u0161an\u0101s resn\u0101s zarnas audos. Tika ne tikai lab\u0101k saglab\u0101ta resn\u0101s zarnas strukt\u016bra, bet ar\u012b iev\u0113rojami samazin\u0101j\u0101s audz\u0113ju slogs.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Darb\u012bbas meh\u0101nisms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>samazina STAT3 fosforil\u0113\u0161anu<\/strong> (centr\u0101lais iekaisuma gad\u012bjum\u0101)<\/li>\n\n\n\n<li><strong>Inhib\u0113 NLRP3 inflammasomu<\/strong> (izmantojot autof\u0101\u0123ijas-lizosomu ce\u013cu)<\/li>\n\n\n\n<li><strong>Pro-iekaisuma citok\u012bnu samazin\u0101\u0161an\u0101s<\/strong><\/li>\n\n\n\n<li>Zarnu barjeras re\u0123ener\u0101cija<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Taj\u0101 pa\u0161\u0101 laik\u0101 samazin\u0101j\u0101s iekaisums UN <a href=\"https:\/\/csiag.eu\/lv\/huaier-senes-veza-terapija\/\" target=\"_blank\" data-type=\"post\" data-id=\"12098\" rel=\"noreferrer noopener\">V\u0113\u017ea risks<\/a> (IBD palielina zarnu v\u0113\u017ea risku!).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Ieteicam\u0101s devas<\/strong>&gt; 0,2 g\/kg \u0137erme\u0146a svara - der\u012bgs \u010d\u016blain\u0101 kol\u012bta un Krona slim\u012bbas gad\u012bjum\u0101.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Differenzierung_Colitis_ulcerosa_vs_Morbus_Crohn\"><\/span>\u010c\u016blain\u0101 kol\u012bta un Krona slim\u012bbas diferenci\u0101cija<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Lokalisation\"><\/span>Lokaliz\u0101cija<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Colitis_ulcerosa_CU\"><\/span><strong>\u010c\u016blainais kol\u012bts (\u010cK)<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Temats <strong>tikai resnaj\u0101 zarn\u0101<\/strong> (resn\u0101s zarnas) un taisn\u0101s zarnas (taisn\u0101s zarnas)<\/li>\n\n\n\n<li>Vienm\u0113r s\u0101kas taisnaj\u0101 zarn\u0101 un nep\u0101rtraukti izplat\u0101s uz aug\u0161u.<\/li>\n\n\n\n<li>Nav \u201el\u0113ciena boj\u0101jumu\u201c<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Morbus_Crohn_MC\"><\/span><strong>Krona slim\u012bba (MC)<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Vai <strong>viss gremo\u0161anas trakts<\/strong> invad\u0113ts (no mutes l\u012bdz an\u0101lam atverim)<\/li>\n\n\n\n<li>Bie\u017ei termin\u0101lais ileums (tiev\u0101s zarnas p\u0113d\u0113jais posms) un resn\u0101 zarna.<\/li>\n\n\n\n<li><strong>Nep\u0101rtraukta inv\u0101zija<\/strong> ar veseliem posmiem starp tiem (\u201eizlaistie boj\u0101jumi\u201c).<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Entzundungstiefe\"><\/span>Iekaisuma dzi\u013cums<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"UC\"><\/span>UC<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Ierobe\u017eots l\u012bdz <strong>G\u013cot\u0101da<\/strong> (g\u013cot\u0101da) un aug\u0161\u0113j\u0101 zem\u0101das da\u013ca<\/li>\n\n\n\n<li>Virspus\u0113js iekaisums<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"MC\"><\/span><strong>MC<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Transmur\u0101ls iekaisums<\/strong> (caur visiem sienu sl\u0101\u0146iem)<\/li>\n\n\n\n<li>Var iek\u013c\u016bt vis\u0101 zarnu sien\u0101<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Allergische_Erkrankungen_Asthma_Allergien\"><\/span>Aler\u0123iskas slim\u012bbas (astma, aler\u0123ijas).<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Huaier ir efekt\u012bvs da\u017e\u0101du ar im\u016bnsist\u0113mu saist\u012btu trauc\u0113jumu, tostarp aler\u0123isku, autoim\u016bnu un infekcijas slim\u012bbu, \u0101rst\u0113\u0161an\u0101. P\u0113t\u012bjum\u0101 <a href=\"https:\/\/portlandpress.com\/bioscirep\/article\/37\/6\/BSR20171071\/57944\/Huai-Qi-Huang-corrects-the-balance-of-Th1-Th2-and\" target=\"_blank\" rel=\"noreferrer noopener\">Peles modelis<\/a> Huaier ekstrakts mazin\u0101ja iekaisuma reakciju elpce\u013cos.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Huai Qi Huang<\/strong> (\u0137\u012bnie\u0161u gar\u0161augu mais\u012bjums, kas <strong>Trametes robiniophila murr (Huaier)<\/strong> kop\u0101 ar vilk\u0101beles aug\u013ciem un poligon\u0101tu (Polygonatum). <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>kav\u0113ja iekaisuma \u0161\u016bnu infiltr\u0101ciju plau\u0161\u0101s.<\/li>\n\n\n\n<li>samazin\u0101ja eozinof\u012blo (EOS), limfoc\u012btu (LYM), neitrof\u012blo (NEU) un makrof\u0101gu (MAC) piepl\u016bdumu bronhoalveol\u0101raj\u0101 skalo\u0161anas \u0161\u0137idrum\u0101 (BALF).<\/li>\n\n\n\n<li>samazin\u0101ts IgE<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u012apa\u0161ais darb\u012bbas meh\u0101nisms:<\/strong> Huai Qi Huang kori\u0123\u0113ja Th1\/Th2 l\u012bdzsvaru ar <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7390013\/\" target=\"_blank\" rel=\"noreferrer noopener\">P\u0113t\u012bjums ar \u017eurku modeli<\/a>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Huai Qi Huang maina T-bet\/Gata-3 un Foxp3\/ROR\u03b3t transkripcijas faktoru mRNS ekspresijas l\u012bmeni, l\u012bdzsvarojot citok\u012bnu profilus un mainot \u0161o transkripcijas faktoru mRNS ekspresijas l\u012bmeni.<\/li>\n\n\n\n<li><strong>Palielin\u0101ts<\/strong> <strong>Foxp3+ <\/strong>\u0161\u016bnas (Treg \u0161\u016bnas)<\/li>\n\n\n\n<li><strong>Samazin\u0101ts Gata-3+<\/strong> \u0161\u016bnas (Th2 \u0161\u016bnas)<\/li>\n\n\n\n<li><strong>Palielina T-bet+<\/strong> \u0161\u016bnas (Th1 \u0161\u016bnas)<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Darb\u012bbas meh\u0101nisms aler\u0123iju gad\u012bjum\u0101:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Darb\u012bbas meh\u0101nisms aler\u0123iju\/astmas gad\u012bjum\u0101 (pamatojoties uz Huai Qi Huang p\u0113t\u012bjumiem):<\/strong><\/li>\n\n\n\n<li><strong>Th2\u2192Th1-shift<\/strong> palielinot T-bet un samazinot Gata-3<\/li>\n\n\n\n<li><strong>Samazina IgE antivielu veido\u0161anos<\/strong> (noz\u012bm\u012bgi izm\u0113r\u012bts serum\u0101)<\/li>\n\n\n\n<li><strong>Samazina Th2 citok\u012bnus<\/strong> (IL-4, IL-5, IL-13)<\/li>\n\n\n\n<li><strong>Palielina Th1 citok\u012bnu daudzumu<\/strong> (IFN-\u03b3, TNF-\u03b1)<\/li>\n\n\n\n<li><strong>Veicina Treg \u0161\u016bnas<\/strong> (Foxp3+) un palielina Treg citok\u012bnus (IL-10, TGF-\u03b21).<\/li>\n\n\n\n<li><strong>Samazina iekaisuma \u0161\u016bnu infiltr\u0101ciju<\/strong> plau\u0161\u0101s (EOS, LYM, NEU, MAC).<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Kardiovaskulare_Erkrankungen\"><\/span>Sirds un asinsvadu slim\u012bbas<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Pa\u0161laik nav public\u0113ti konkr\u0113ti kl\u012bniskie p\u0113t\u012bjumi par \u0161\u012bm indik\u0101cij\u0101m. Tom\u0113r viens <a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.125.041405\" target=\"_blank\" rel=\"noreferrer noopener\">P\u0113t\u012bjums<\/a> Amerikas Sirds asoci\u0101cijas (JAHA) ar <strong>Plau\u0161u hipertensija<\/strong> (PH) grauz\u0113ju mode\u013cos.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Iesp\u0113jamais darb\u012bbas meh\u0101nisms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Huaier <strong>nom\u0101c HIF1\u03b1 <\/strong>(hipoksiju induc\u0113jo\u0161\u0101 faktora) signaliz\u0101cijas ce\u013c\u0161<\/li>\n\n\n\n<li><strong>inhib\u0113 NF-\u03baB<\/strong> (mazina iekaisumu)<\/li>\n\n\n\n<li><strong>Aktiviz\u0113 Nrf2<\/strong> (aktiviz\u0113 \u0161\u016bnas pa\u0161u atjauno\u0161anas programmu ar vair\u0101k nek\u0101 200 g\u0113niem, kuru ekspresijai).<br><strong>Antioksidanti<\/strong> (SOD2, katal\u0101ze, glutations)<br>- Neitraliz\u0113 br\u012bvos radik\u0101\u013cus<br><strong>Detoksik\u0101cijas enz\u012bmi<\/strong> (glutationa S-transfer\u0101ze u. c.)<br>- Padara toks\u012bnus \u0161\u0137\u012bsto\u0161us \u016bden\u012b un izvad\u0101mus.<br><strong>Mitohondriju remonta prote\u012bni<\/strong> (NRF1, TFAM)<br>- salabot \u0161\u016bnas ener\u0123ijas sp\u0113kstacijas<br>- \u0160\u016bna atkal ra\u017eo ATP (ener\u0123iju)<\/li>\n\n\n\n<li>uzlabo mitohondriju darb\u012bbu<\/li>\n\n\n\n<li>mazina oksidat\u012bvo stresu<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Neurodegenerative_Erkrankungen_%E2%80%93_Parkinson\"><\/span>Neirode\u0123enerat\u012bvas slim\u012bbas - Parkinsona slim\u012bba<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Gad\u012bjuma izp\u0113te <a href=\"https:\/\/www.academia.edu\/en\/49416761\/Huaier_Compensates_Impaired_Signal_Transfer_Inter_Intra_Neurons_in_Central_and_Peripheral_Nervous_Systems\" target=\"_blank\" rel=\"noreferrer noopener\">Huaier kompens\u0113 trauc\u0113tu sign\u0101lu p\u0101rnesi starp neironiem centr\u0101laj\u0101 un perif\u0113raj\u0101 nervu sist\u0113m\u0101<\/a> Tanaka e.a. apraksta pacienta ar Parkinsona slim\u012bbu veiksm\u012bgu atvese\u013co\u0161anos.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Teor\u0113tiskais darb\u012bbas meh\u0101nisms saist\u012bb\u0101 ar visp\u0101r\u0113j\u0101m neirode\u0123enerat\u012bv\u0101m slim\u012bb\u0101m:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Pretiekaisuma l\u012bdzeklis<\/strong> (neirode\u0123enerat\u012bvo slim\u012bbu pamat\u0101 ir neirode\u0123enerat\u012bvas iekaisuma slim\u012bbas).<\/li>\n\n\n\n<li><strong>Antioksidants<\/strong> (aizsarg\u0101 pret neironu de\u0123ener\u0101ciju)<\/li>\n\n\n\n<li><strong>Neiroprotekt\u012bvs<\/strong> (aktiviz\u0113jot aug\u0161anas faktorus)<\/li>\n\n\n\n<li><strong>Aktiviz\u0113 mikroglijas polariz\u0101ciju<\/strong> (no pro- uz pretiekaisuma)<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Statuss:<\/strong> Attiec\u012bgi kl\u012bniskie p\u0113t\u012bjumi ar cilv\u0113kiem v\u0113l nav pieejami.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Postinfektiose_Syndrome\"><\/span>P\u0113cinfekcijas sindromi<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Gar\u0101 COVID patofiziolo\u0123ija:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Past\u0101v\u012bga im\u016bn\u0101 aktiv\u0101cija (Th1\/Th17 dominance)<\/li>\n\n\n\n<li>V\u012brusa perzistence (limf\u0101tiskajos audos\/p\u0101rk\u0101tuves trakt\u0101)<\/li>\n\n\n\n<li>Mikroglijas aktiviz\u0113\u0161an\u0101s<\/li>\n\n\n\n<li>Notur\u012bgi endot\u0113lija boj\u0101jumi<\/li>\n\n\n\n<li>Notur\u012bgs neirona iekaisums<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Teor\u0113tisks darb\u012bbas meh\u0101nisms (nav pier\u0101d\u012bts ar p\u0113t\u012bjumiem):<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Imunoregul\u0101cija:<\/strong> normaliz\u0113 Th1\/Th17 l\u012bdzsvaru<\/li>\n\n\n\n<li><strong>Pretv\u012brusu iedarb\u012bba:<\/strong> Aktiviz\u0113 NK \u0161\u016bnas un CD8+ T \u0161\u016bnas<\/li>\n\n\n\n<li><strong>Pretiekaisuma l\u012bdzeklis:<\/strong> Samazina notur\u012bgu citok\u012bnu veido\u0161anos<\/li>\n\n\n\n<li><strong>Endot\u0113lija aizsardz\u012bba:<\/strong> Antioksidants, nov\u0113r\u0161 turpm\u0101kus boj\u0101jumus<\/li>\n<\/ol>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Mogliche_Rolle_nach_mRNA-Vakzinationen\"><\/span>Iesp\u0113jam\u0101 loma p\u0113c mRNS vakcin\u0101cijas<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Sav\u0101 2023. gad\u0101 public\u0113taj\u0101 p\u0113t\u012bjum\u0101 jap\u0101\u0146u p\u0113tnieki, kurus vad\u012bja Tanaka u.c., nov\u0113roja, ka <a href=\"https:\/\/www.bradeion.com\/wp\/wp-content\/uploads\/2023\/01\/Abstract-Huaier-Effects-on-Prevention-and-Inhibition-of-Spontaneous-SARS-CoV-2-Virion-Production-b.html\" target=\"_blank\" rel=\"noreferrer noopener\">Huaier ietekme uz SARS-CoV-2 v\u012brusu spont\u0101nas veido\u0161an\u0101s nov\u0113r\u0161anu un kav\u0113\u0161anu ar atk\u0101rtotu Pfizer-BioNTech mRNS vakcin\u0101ciju<\/a>, ka pacientiem, kuri p\u0113c vakcin\u0101cijas regul\u0101ri lietoja Huaier, iev\u0113rojami ret\u0101k sastopami v\u0113\u017ea recid\u012bvi un kopum\u0101 tie \u0101tr\u0101k atvese\u013coj\u0101s. Da\u017eiem pacientiem asin\u012bs vairs nevar\u0113ja konstat\u0113t pat eso\u0161\u0101s smailes olbaltumvielas.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Iepriek\u0161\u0113jais p\u0113t\u012bjums, kas veikts 2022. gad\u0101 <a href=\"https:\/\/www.researchgate.net\/publication\/362973345_Huaier_Effects_on_Functional_Compensation_with_Destructive_Ribosomal_RNA_Structure_after_Anti-SARS-CoV-2_mRNA_Vaccination\" target=\"_blank\" rel=\"noreferrer noopener\">Huaier ietekme uz funkcion\u0101lo kompens\u0101ciju ar destrukt\u012bvo ribosom\u0101l\u0101s RNS strukt\u016bru p\u0113c anti-SARS-CoV-2 mRNS vakcin\u0101cijas<\/a> analiz\u0113 ribosom\u0101l\u0101s RNS strukt\u016bru p\u0113c mRNS vakcin\u0101cijas IV stadijas v\u0113\u017ea pacientiem p\u0113c vakcin\u0101cijas.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Vi\u0146i secin\u0101ja, ka Huaier granulu lieto\u0161ana<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>maz\u0101k veidoj\u0101s smailes olbaltumvielu (m\u0113r\u012bts, izmantojot RNS sekven\u0113\u0161anu).<\/li>\n\n\n\n<li>bija lab\u0101ka ribosom\u0101l\u0101s RNS strukt\u016bra.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Iesp\u0113jamie meh\u0101nismi:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Ribosom\u0101l\u0101s RNS funkcijas atbalsts (p\u0113c vakcin\u0101cijas boj\u0101juma; saska\u0146\u0101 ar gad\u012bjumu zi\u0146ojumu).<\/li>\n\n\n\n<li>Past\u0101v\u012bgu smailes prote\u012bnu ra\u017eo\u0161anas samazin\u0101\u0161ana (pretrun\u012bgi v\u0113rt\u0113jama k\u0101 mainstream).<\/li>\n\n\n\n<li>Im\u016bnregul\u0101cija p\u0113c p\u0101rm\u0113r\u012bgas stimul\u0101cijas<\/li>\n\n\n\n<li>Iekaisuma kav\u0113\u0161ana<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Chronische_Lebererkrankungen_%E2%80%93_Hepatozellulares_Karzinom_HCC\"><\/span>Hroniskas aknu slim\u012bbas - Hepatocelul\u0101r\u0101 karcinoma (HCC)<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Chen Q, Shu C un citu autoru veiktais nejau\u0161in\u0101ts kontrol\u0113ts p\u0113t\u012bjums.<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29793986\/\" target=\"_blank\" rel=\"noreferrer noopener\"> Huaier granulu ietekme uz recid\u012bvu p\u0113c HCC \u0101rstnieciskas rezekcijas<\/a> no 2018. gada aprakst\u012bti rezult\u0101ti p\u0113c 20 g Huaier granulu lieto\u0161anas 3 reizes dien\u0101 96 ned\u0113\u013cas p\u0113c rezekcijas, p\u0113t\u012bjum\u0101 piedal\u012bj\u0101s 696 pacienti.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Darb\u012bbas meh\u0101nisms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Samazina malondialdeh\u012bda daudzumu<\/strong> (MDA) - oksidat\u012bv\u0101 stresa mar\u0137ieris<\/li>\n\n\n\n<li><strong>palielina superoks\u012bda dismut\u0101zi<\/strong> (SOD) - antioksidants<\/li>\n\n\n\n<li><strong>palielina katal\u0101zes saturu<\/strong> (CAT) - antioksidants<\/li>\n\n\n\n<li><strong>palielina glutationa daudzumu<\/strong> (GSH) - galvenais antioksidants<\/li>\n\n\n\n<li><strong>Aktiviz\u0113 PI3K\/AKT\/Nrf2 signaliz\u0101cijas ce\u013cu<\/strong> (Western blotting + qRT-PCR)<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Das_universelle_Wirkprinzip_von_Huaier\"><\/span>Huaier univers\u0101lais darb\u012bbas princips<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Huaier regul\u0113 vair\u0101kas imunolo\u0123isk\u0101s atbildes reakcijas, s\u0101kot no ar boj\u0101jumu saist\u012bto molekul\u0101ro mode\u013cu ekspresijas, im\u016bno \u0161\u016bnu aktiviz\u0101cijas un nobrie\u0161anas l\u012bdz \u0161\u016bnu prolifer\u0101cijai, diferenci\u0101cijai, antivielu veido\u0161anai, citok\u012bnu un hemok\u012bnu ekspresijai un termin\u0101lajai intracelul\u0101rajai signaliz\u0101cijai.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Galven\u0101 koncepcija: da\u017eas Huaier modul\u0113jo\u0161\u0101s darb\u012bbas var b\u016bt atkar\u012bgas no konteksta, parasti veicinot norm\u0101la fiziolo\u0123isk\u0101 st\u0101vok\u013ca atjauno\u0161anos.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Vienk\u0101r\u0161\u0101k sakot, Huaier nedarbojas k\u0101 z\u0101les, kas blo\u0137\u0113 konkr\u0113tu funkciju. T\u0101 viet\u0101 Huaier atgrie\u017e im\u016bnsist\u0113mu atpaka\u013c l\u012bdzsvar\u0101 un norm\u0101l\u0101 st\u0101vokl\u012b (<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10337589\/\" target=\"_blank\" rel=\"noreferrer noopener\">Avots:<\/a>).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Signalweg-Architektur\"><\/span>Sign\u0101la ce\u013ca arhitekt\u016bra<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Huaier iedarbojas uz \u0161\u0101diem centr\u0101lajiem signaliz\u0101cijas ce\u013ciem:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Sign\u0101la ce\u013c\u0161<\/th><th>Parasts<\/th><th>Hronisk\u0101m slim\u012bb\u0101m<\/th><th>Huaier efekts<\/th><\/tr><\/thead><tbody><tr><td><strong>PI3K\/AKT\/mTOR<\/strong><\/td><td>M\u0113rena aktivit\u0101te<\/td><td>Hiperakt\u012bvs (iekaisums)<\/td><td>Normaliz\u0101cija<\/td><\/tr><tr><td><strong>JAK2\/STAT3<\/strong><\/td><td>Regul\u0113ts<\/td><td>Past\u0101v\u012bga aktiviz\u0113\u0161ana<\/td><td>Samazina fosforil\u0113\u0161anu<\/td><\/tr><tr><td><strong>NF-\u03baB<\/strong><\/td><td>B\u0101zes + aktiviz\u0113jams<\/td><td>Konstitut\u012bvi akt\u012bvs<\/td><td>Atgrie\u0161an\u0101s pie pamatl\u012bme\u0146a<\/td><\/tr><tr><td><strong>Hippo\/YAP<\/strong><\/td><td>Akt\u012bva (kontrole)<\/td><td>Inhib\u0113ts (nekontrol\u0113ts)<\/td><td>Reaktiviz\u0113ts<\/td><\/tr><tr><td><strong>MAPK (ERK\/p38)<\/strong><\/td><td>Piel\u0101gots<\/td><td>P\u0101rm\u0113r\u012bgi akt\u012bvs<\/td><td>Normaliz\u0101cija<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dosierung_bei_chronischen_Erkrankungen\"><\/span>Devas hronisk\u0101m slim\u012bb\u0101m<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Dosierungen von Huaier sind NICHT grunds\u00e4tzlich abh\u00e4ngig vom K\u00f6rpergewicht und bed\u00fcrfen somit i.d.R. auch keiner Anpassung, da die Wirkung nicht von der Konzentration im Blut (wie z.B. Antibiotika)abh\u00e4ngig ist, sondern Signalwege adressiert und dar\u00fcber die beabsichtigten Wirkungen induziert werden.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Nor\u0101de<\/th><th>Doz\u0113\u0161ana<\/th><th>Ilgums<\/th><th>\u012apa\u0161\u0101s iez\u012bmes<\/th><\/tr><\/thead><tbody><tr><td><strong>Hronisks iekaisums<\/strong><\/td><td>10-15 g\/dien\u0101<\/td><td>3-6 m\u0113ne\u0161i<\/td><td>Nep\u0101rtraukts<\/td><\/tr><tr><td><strong>Autoim\u016bna slim\u012bba<\/strong><\/td><td>10-15 g\/dien\u0101<\/td><td>6-12 m\u0113ne\u0161i+<\/td><td>Ilgtermi\u0146a uz\u0146em\u0161ana<\/td><\/tr><tr><td><strong>Aler\u0123iskas slim\u012bbas<\/strong><\/td><td>10-15 g\/dien\u0101<\/td><td>Sezon\u0101ls vai nep\u0101rtraukts<\/td><td>Atbalsta<\/td><\/tr><tr><td><strong>V\u0113\u017ea profilakse<\/strong> (IBD, hepat\u012bts)<\/td><td>5-10 g\/dien\u0101<\/td><td>Nep\u0101rtraukts<\/td><td>Ilgtermi\u0146a profilakse<\/td><\/tr><tr><td><strong>P\u0113c-COVID\/Post-Vac<\/strong><\/td><td>10-15 g\/dien\u0101<\/td><td>3-12 m\u0113ne\u0161i<\/td><td>Individu\u0101li atkar\u012bgs<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Visp\u0101r\u012bgi:<\/strong> Hronisku slim\u012bbu gad\u012bjum\u0101 devas bie\u017ei vien ir maz\u0101kas nek\u0101 akt\u012bva v\u0113\u017ea gad\u012bjum\u0101, bet ilg\u0101ka termi\u0146a.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Sicherheit_und_Vertraglichkeit\"><\/span>Dro\u0161\u012bba un sader\u012bba<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Blakuspar\u0101d\u012bbu profils:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u013boti zems<\/li>\n\n\n\n<li>Atsevi\u0161\u0137as \u201edetoksik\u0101cijas reakcijas\u201c 1.-2. ned\u0113\u013c\u0101<\/li>\n\n\n\n<li>Nav zin\u0101mas nopietnas nepanes\u012bbas<\/li>\n\n\n\n<li>\u013boti labs dro\u0161\u012bbas profils<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Kontrindik\u0101cijas:<\/strong> Nav zin\u0101ms (iz\u0146emot, iesp\u0113jams, da\u017eus asins rec\u0113\u0161anas trauc\u0113jumus).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Anmerkung\"><\/span>Piez\u012bme<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Hronisku slim\u012bbu p\u0113tniec\u012bbas statuss:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Lai gan pier\u0101d\u012bjumi par v\u0113zi (\u012bpa\u0161i HCC un kr\u016bts v\u0113zi) ir \u013coti p\u0101rliecino\u0161i, p\u0113t\u012bjumi par cit\u0101m hronisk\u0101m slim\u012bb\u0101m joproj\u0101m nav viennoz\u012bm\u012bgi.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Hunaiers hronisku slim\u012bbu gad\u012bjum\u0101 ir j\u0101uzskata par papildu l\u012bdzekli (nevis aizst\u0101j\u0113ju) tradicion\u0101lajai medic\u012bnai.<\/p>","protected":false},"excerpt":{"rendered":"<p><span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Las\u012b\u0161anas laiks<\/span> <span class=\"rt-time\"> 5<\/span> <span class=\"rt-label rt-postfix\">protokols<\/span><\/span>Der Huaier-Pilz bei chronischen Erkrankungen &#8211; Wissenschaftliche Studien, Indikationen und Wirkmechanismen Daten aus Aktueller Forschung belegen, dass Huaier auch bei Autoimmunerkrankungen, chronischen Entz\u00fcndungen, kardiovaskul\u00e4ren Erkrankungen, neurodegenerativen St\u00f6rungen und postinfekti\u00f6sen Syndromen wie ME\/CFS oder Post-Vac-Syndrom vielversprechend ist. Huaier besitzt sog. &#8222;broad-spectrum regulatory activities&#8220; auf verschiedene Komponenten des angeborenen und adaptiven Immunsystems, einschlie\u00dflich der Makrophagen, dendritischen Zellen,&hellip;&nbsp;<a href=\"https:\/\/csiag.eu\/lv\/blog\/2026\/01\/11\/huaier-pilz-bei-chronischen-erkrankungen\/\" rel=\"bookmark\">Las\u012bt vair\u0101k \"<span class=\"screen-reader-text\">Huaier s\u0113ne hronisk\u0101m slim\u012bb\u0101m<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"","neve_meta_content_width":0,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-12205","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"modified_by":"Achim Goerner","_links":{"self":[{"href":"https:\/\/csiag.eu\/lv\/wp-json\/wp\/v2\/posts\/12205","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/csiag.eu\/lv\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csiag.eu\/lv\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csiag.eu\/lv\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/csiag.eu\/lv\/wp-json\/wp\/v2\/comments?post=12205"}],"version-history":[{"count":0,"href":"https:\/\/csiag.eu\/lv\/wp-json\/wp\/v2\/posts\/12205\/revisions"}],"wp:attachment":[{"href":"https:\/\/csiag.eu\/lv\/wp-json\/wp\/v2\/media?parent=12205"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csiag.eu\/lv\/wp-json\/wp\/v2\/categories?post=12205"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csiag.eu\/lv\/wp-json\/wp\/v2\/tags?post=12205"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}